Egtazic acid CAS:67-42-5 Kumukūʻai Mea Hana

Calcium chelation: He kiʻekiʻe ko EGTA no nā ion calcium a hiki ke hoʻopaʻa pono iā lākou, e hōʻemi ana i ka neʻe o ka calcium manuahi i loko o kahi hopena.Hoʻohana kēia waiwai iā EGTA i ke aʻo ʻana i ke kuleana o ka calcium i nā ʻano hana olaola like ʻole.

Hoʻohana pinepine ʻia ʻo EGTA no ka hana ʻana i ka calcium-free a i ʻole ka haʻahaʻa calcium buffer no nā hoʻokolohua.Ma ka chelating calcium, kōkua ʻo EGTA i ka mālama ʻana i ka manaʻo i makemake ʻia o nā ion calcium i ka hopena, e ʻae ana i nā mea noiʻi e hoʻomalu i nā hopena pili i ka calcium.

ʻO ka hoʻololi ʻana i ka hana enzyme: Nui nā enzyme e koi i nā ion metala kūikawā, me ka calcium, no kā lākou hana.Hiki ke hoʻohana ʻia ʻo EGTA no ka hoʻololi ʻana i ka hana enzyme ma o ka chelating a me ka wehe ʻana i kēia mau ion metala mai ka hui ʻana.

Hoʻokaʻawale pūnaewele: He mea pono ka EGTA i ka dissociation cell a me nā kaʻina hana hoʻokaʻawale.Kōkua ia i ka uhaki ʻana o ka cell-cell a me ka cell-extracellular matrix matrix ma ka chelating calcium-dependent adhesion molecules, e alakaʻi ana i ka detachment o nā cell.

Nā haʻawina hōʻailona calcium: ʻO ka hiki i ka EGTA ke chelate i nā ion calcium he mea maikaʻi no nā haʻawina hōʻailona calcium.Ma ka hoʻomalu ʻana i ka neʻe ʻana o nā ion calcium manuahi me EGTA, hiki i nā mea noiʻi ke loiloi pololei i ka hana o ka calcium i ka hōʻailona intracellular a me nā kaʻina hana physiological ʻē aʻe.

Nā ʻenehana biology molecular: Hoʻohana ʻia ʻo EGTA i nā ʻano hana biology molecular e like me DNA a me RNA extraction, hoʻomaʻemaʻe protein, a me nā hoʻāʻo enzyme.Kōkua ia i ka hoʻopaʻa ʻana i nā ʻakika nucleic a me nā protein ma ka pale ʻana i ka degradation metala-ion mediated.

Moʻomeheu kelepona: Hoʻohana mau ʻia ʻo EGTA i ka moʻomeheu cell no ka mālama ʻana i nā haʻahaʻa haʻahaʻa o ka calcium e aʻo pololei i nā kaʻina kelepona pili i ka calcium.Hoʻomaʻamaʻa ia i ka lawe ʻia ʻana o ka calcium mai ka media ulu, e ʻae ana i nā mea noiʻi e noiʻi i ke kuleana o ka calcium i loko o ka biology cell.