ʻAkika Egtazic CAS: 67-42-5 Kumukūʻai Mea Hana

Ka hoʻopili ʻana o ka calcium: Loaʻa iā EGTA kahi pilina kiʻekiʻe no nā ion calcium a hiki ke hoʻopaʻa pono iā lākou, e hōʻemi ana i ka nui o ka calcium manuahi i loko o kahi hopena. ʻO kēia waiwai e lilo ai ʻo EGTA i mea pono i ke aʻo ʻana i ke kuleana o ka calcium i nā kaʻina hana olaola like ʻole.

ʻO ka pale calcium: Hoʻohana pinepine ʻia ʻo EGTA e hana i nā pale calcium ʻole a haʻahaʻa paha no nā hoʻokolohua. Ma ka chelating calcium, kōkua ʻo EGTA i ka mālama ʻana i kahi nui o nā ion calcium i makemake ʻia i loko o ka hopena, e ʻae ana i nā mea noiʻi e kāohi i nā hopena e pili ana i ka calcium.

Hoʻololi ʻana i ka hana enzyme: Pono nā enzyme he nui i nā ion metala kikoʻī, me ka calcium, no kā lākou hana. Hiki ke hoʻohana ʻia ʻo EGTA e hoʻololi i ka hana enzyme ma o ka chelating a me ka wehe ʻana i kēia mau ion metala e pono ai mai ka hui hopena.

Ka hoʻokaʻawale ʻana o ke kelepona: He mea pono ka EGTA i nā kaʻina hana hoʻokaʻawale ʻana o ke kelepona a me ka hoʻokaʻawale ʻana o nā ʻiʻo. Kōkua ia i ka uhaki ʻana i nā pilina matrix cell-cell a me cell-extracellular ma o ka chelating calcium-dependent adhesion molecules, e alakaʻi ana i ka hoʻokaʻawale ʻana o nā kelepona.

Nā haʻawina hōʻailona kalipuna: ʻO ka hiki o EGTA ke chelate i nā ion kalipuna he mea maikaʻi ia no nā haʻawina hōʻailona kalipuna. Ma ka kaohi ʻana i ka nui o nā ion kalipuna manuahi me EGTA, hiki i nā mea noiʻi ke loiloi pololei i ke kuleana o ka kalipuna i ka hōʻailona intracellular a me nā kaʻina hana physiological ʻē aʻe.

Nā ʻenehana biology molekala: Hoʻohana ʻia ʻo EGTA i nā ʻenehana biology molekala like ʻole e like me ka unuhi ʻana o ka DNA a me ka RNA, ka hoʻomaʻemaʻe ʻana i ka protein, a me nā hoʻāʻo enzyme. Kōkua ia i ka hoʻopaʻa ʻana i nā waikawa nucleic a me nā protein ma ka pale ʻana i ka hoʻohaʻahaʻa ʻia e ka metal-ion.

Moʻomeheu kelepona: Hoʻohana pinepine ʻia ʻo EGTA i ka moʻomeheu kelepona e mālama i nā pae haʻahaʻa o ka calcium e aʻo pono i nā kaʻina hana kelepona e pili ana i ka calcium. Hoʻomaʻalahi ia i ka wehe ʻana o ka calcium mai nā mea ulu, e ʻae ana i nā mea noiʻi e noiʻi i ke kuleana o ka calcium i loko o ke olaola kelepona.