Mirabegron CAS:223673-61-8 Mea Hana Mea Hoʻolako Kiʻi Hōʻikeʻike

Mirabegron CAS:223673-61-8 Mea Hoʻolako Mea Hana

ʻO Mirabegron no ka mālama ʻana i ka wikiwiki, ka pinepine ʻana o ka mimi, a me ka hoʻoikaika ʻana i ka urinary incontinence e pili ana me ka overactive bladder (OAB).Hoʻopili ʻia ʻo Mirabegron ma o ka hoʻohui ʻana i ka 4-nitrophenethyl amine i (R) -2-hydroxy-2-phenylacetic acid.Hoʻemi ʻia ka amide hopena i kahi amine.Hoʻemi ʻia ka hui nitro a hoʻohui ʻia ka hopena i ka 2-(2-aminothiazol-4-yl) acetic acid e hāʻawi ai i ka mirabegron.

Kauoha a Noi Manao

Huahana Huahana

Hoʻohana a me ka hopena

ʻO Mirabegron kahi agonist β3-adrenoceptor olly active i kēia manawa e hoʻomohala ʻia e Astellas Pharma no ka mālama ʻana i ka ʻōpū overactive (OAB).ʻO ka lāʻau lapaʻau he mea kū'ē kū'ē i ka β3-AR biochemical assays nanomolar EC50 me ka koho maikaʻi ma luna o b1- a me β2-ARs.Hōʻike ʻo Mirabegron i kahi hana hou ma ka huli ʻana i ka β3-AR no ka hoʻomaha ʻana i ka ʻōpū e kōkua i ka hoʻokele ʻana i nā hōʻailona OAB e like me ka hoʻonui ʻana i ka mimi a me ka pinepine a me ka wikiwiki ʻole.Eia nō naʻe, ʻo ka mirabegron he cytochrome P450 2D6 inhibitor, a hoʻāla ia i kahi hopohopo no ka pilina lāʻau-lāʻau me ka hoʻokele like ʻana o nā substrate cytochrome P450 2D6.

Laʻana Huahana

Hoʻopili huahana:

ʻIke hou aku:

Huina	C21H24N4O2S
Hoʻāʻo	99%
Ka nana aku	Keokeo a Pale Melemele pauda
CAS No.	223673-61-8
Hoʻopili	25KG
Ola Pahu	2 makahiki
Waihona	E mālama ma kahi maloʻo a maloʻo
Palapala hōʻoia	ISO.