Mirabegron CAS:223673-61-8 Mea Hana Mea Hoʻolako

ʻO Mirabegron no ka mālama ʻana i ka wikiwiki, ka pinepine o ka mimi, a me ka makemake ʻole o ka mimi e pili ana me ka ʻōpū mimi overactive (OAB). Hoʻohui ʻia ʻo Mirabegron ma ka hoʻopili ʻana i ka 4-nitrophenethyl amine i ka (R)-2-hydroxy-2-phenylacetic acid. Hoʻemi ʻia ka amide hopena i amine. A laila hoʻemi ʻia ka hui nitro a hoʻopili ʻia ka hopena i ka 2-(2-aminothiazol-4-yl) acetic acid e hāʻawi i ka mirabegron.

Kauoha a Noi paha i ka ʻŌlelo Kūʻai

Nā kikoʻī huahana

Nā Lepili Huahana

Hoʻohana a me ka hopena

He agonist β3-adrenoceptor hana waha ʻo Mirabegron e hoʻomohala ʻia nei e Astellas Pharma no ka mālama ʻana i ka ʻōpū mimi overactive (OAB). He antagonist nanomolar EC50 kēia lāʻau e kūʻē i nā hoʻāʻo biochemical β3-AR kanaka me ke koho maikaʻi ma luna o b1- a me β2-AR. Hōʻike ʻo Mirabegron i kahi ʻano hana hou ma o ka hoʻopaʻa ʻana i ka β3-AR no ka hoʻomaha ʻana o ka ʻōpū mimi e kōkua i ka hoʻokele ʻana i nā hōʻailona OAB e like me ka hoʻonui ʻia o ka wikiwiki o ka mimi a me ka pinepine a me ka incontinence wikiwiki. Eia nō naʻe, he mea hoʻopaʻa cytochrome P450 2D6 ʻo mirabegron, a ke hāpai nei ia i kahi hopohopo no ka launa pū ʻana o ka lāʻau me ka hoʻokele like ʻana o nā substrates cytochrome P450 2D6 ʻē aʻe.

Laʻana Huahana

Hoʻopili Huahana:

ʻIke Hou Aʻe:

Hoʻonohonoho ʻana	C21H24N4O2S
Hoʻāʻo	99%
helehelena	Pauka keʻokeʻo a melemele māmā
Helu CAS.	223673-61-8
Hoʻopili ʻana	25KG
Ola Papa	2 mau makahiki
Ka Waihona	E mālama i kahi maloʻo a me kahi anuanu
Palapala hōʻoia	ISO.