Sitagliptin Phosphate CAS:654671-78-0 Mea Hoʻolako Mea Hana

ʻO Sitagliptin Phosphate kahi trizolopyrazine dipeptidyl peptidase IV inhibitor.Ua ʻae ʻia ʻo Sitagliptin no ka mālama ʻana i ka maʻi diabetes type II. ʻO Sitagliptin phosphate ka dipeptidyl peptidase Ⅳ(DDP-4) papa inhibitor o nā lāʻau lapaʻau i hoʻomohala ʻia e ka hui German Merck a loaʻa mua i ka US Food and Drug Administration apono no ka mālama ʻana i ke ʻano 2. ʻO ka maʻi diabetes, he lāʻau antidiabetic hou, hiki ke hoʻomaikaʻi i ke kino ponoʻī e hōʻemi i nā pae glucose koko kiʻekiʻe, a me ka piʻi ʻana o ka incretin kūlohelohe ma ke kāohi ʻana i ka hana o kēia enzyme, me nā pae o ka glucagon-like peptide 1 a me ka glucose-dependent insulinotropic. peptide, ma laila e hoʻoulu ai i ka pancreas e hoʻomaikaʻi i ka hana ʻana o ka insulin a hoʻōki i ka hana ʻana o ka glucose i loko o ke akepaʻa, a hoʻemi hope i ka hopena lapaʻau o ke koko glucose.