ʻO Sitagliptin Phosphate CAS:654671-78-0 Mea Hana Mea Hoʻolako

ʻO Sitagliptin Phosphate kahi mea hoʻopaʻa trizolopyrazine dipeptidyl peptidase IV. Ua ʻae ʻia ʻo Sitagliptin no ka mālama ʻana i ka maʻi diabetes type II. ʻO Sitagliptin phosphate ka papa lāʻau hoʻopaʻa dipeptidyl peptidase Ⅳ (DDP-4) i hoʻomohala ʻia e ka hui Kelemania Merck a ua loaʻa mua ka ʻae ʻia e ka US Food and Drug Administration no ka mālama ʻana i ka maʻi diabetes type 2, he lāʻau antidiabetic hou, hiki ke hoʻomaikaʻi i ka hiki o ke kino ke hoʻemi i nā pae glucose koko kiʻekiʻe, a me ka hoʻonui iki ʻana o ka incretin kūlohelohe ma ke kāohi ʻana i ka hana o kēia enzyme, me nā pae o ka glucagon-like peptide 1 a me ka glucose-dependent insulinotropic peptide, no laila e hoʻoulu ai i ka pancreas e hoʻomaikaʻi i ka hana ʻana o ka insulin a hoʻōki i ka hana ʻana o ka glucose i loko o ke ake, a i ka hopena e hoʻemi i ka hopena lapaʻau o ka nui o ka glucose koko.