Sodium Alpha-Ketoisocaproate CAS:4502-00-5 Mea Hoʻolako Mea Hana

ʻO ka Sodium Alpha-Ketoisocaproate kahi metabolite leucine i ʻike ʻia e hoʻoulu i ka huna ʻana o ka insulin mai nā βcells o ka pancreas.ʻIke ʻia ka infusion enteral o aα-Ketoisocaproate e hoʻomaikaʻi i ke kūlana endotoxemic.ʻO nā kino ketone i loaʻa mai kona hoʻololi ʻana, hiki ke lilo i kumu ikehu.Hōʻike ʻia ka hōʻiliʻili ʻana o ka waika α-Ketoisocaproic i ka ketoaciduria kaulahao branched, ka mea i hana ʻia ma muli o ka nele o ka hana L-2-keto acid dehydrogenase.ʻO ka α-Ketoisocaproic acid ka mea e hoʻokaʻawale ai i ka hopena o ka phosphorylation oxidative a hana ma ke ʻano he mea hoʻokae metabolic o ka α-ketoglutarate dehydrogenase.No laila, ke alakaʻi nei i kahi kīnā i ka homeostasis mitochondrial, i ʻike ʻia i ke kaulahao lālā ketoaciduria.