Sodium Alpha-Ketoisocaproate CAS:4502-00-5 Mea Hana Mea Hoʻolako

ʻO Sodium Alpha-Ketoisocaproate kahi metabolite leucine i ʻike ʻia e hoʻoulu i ka hoʻokuʻu ʻana o ka insulin mai nā βcells o ka pancreas. ʻIke ʻia ka hoʻokomo ʻana o aα-Ketoisocaproate i loko o ka enteral e hoʻomaikaʻi i ke kūlana endotoxemic. ʻO nā kino ketone i loaʻa mai kona hoʻololi ʻana, hiki ke lawelawe ma ke ʻano he kumu ikehu. ʻO ka hōʻiliʻili ʻana o ka waikawa α-Ketoisocaproic i hōʻike ʻia i loko o ke ketoaciduria kaulahao branched, i hana ʻia ma muli o ka nele o ka hana dehydrogenase waikawa L-2-keto branched. Hoʻoulu ka waikawa α-Ketoisocaproic i ka dissociation i ka hopena phosphorylation oxidative a hana ma ke ʻano he mea hoʻopaʻa metabolic o α-ketoglutarate dehydrogenase. No laila, alakaʻi i kahi hemahema i ka homeostasis mitochondrial, i ʻike ʻia ma ke ketoaciduria kaulahao branched.