α-Galactosidase CAS:9025-35-8

α-galactosidaseʻO (α-galactosidase, α-gal, EC 3.2.1.22) he exoglycosidase e hoʻoulu ai i ka hydrolysis o nā pilina α-galactosidic. Ma muli o ka hiki iā ia ke hoʻokaʻawale i ka melibiose, ua kapa ʻia hoʻi ʻo melibiase, kahi e hoʻoulu ai i ka hydrolysis o nā pilina α-galactosidic. ʻO kēia hiʻohiʻona e lilo ia i mea pono no ka hoʻomaikaʻi ʻana a me ka hoʻopau ʻana i nā ʻāpana anti-nutritional i loko o nā meaʻai hānai a me nā meaʻai soy. Eia kekahi, hiki iā ia ke hoʻomaopopo i ka hoʻololi ʻana o ke ʻano koko B→O ma ke kahua lapaʻau, hoʻomākaukau i ke koko honua, a pāʻani i kahi kuleana koʻikoʻi i ka hoʻōla enzyme o ka maʻi Fabry. Hiki i ka α-galactosidase ke hana ma nā polysaccharides paʻakikī, glycoproteins a me glycosphingoses e loaʻa ana nā pilina α-galactosidic. Hiki i kekahi mau α-galactosidases ke transgalactosylate i ka wā e hoʻonui nui ʻia ai ka nui o ka substrate, a hiki ke hoʻohana ʻia kēia hiʻohiʻona no ka synthesis o oligosaccharides a me ka hoʻomākaukau ʻana o nā cyclodextrin derivatives. ʻO ka hoʻomohala ʻana o ka neutrophil a i ʻole ka pH-stable α-galactosidase a me ka ʻimi ʻana i nā microorganism a i ʻole nā ​​​​mea kanu me ka hana enzyme kiʻekiʻe ua lilo i mau wahi noiʻi i nā makahiki i hala iho nei. Ua hoʻāla mālie nā α-galactosidases he nui i ka hoihoi ākea o nā kānaka ʻepekema ma muli o ko lākou ʻano kūikawā, me ka manaʻo e hoʻohana i ko lākou kūpaʻa wela e pāʻani i kahi waiwai hoʻohana nui aʻe i ka ʻoihana, a e hōʻike i kahi ākea o nā noi ma nā kahua o ka ʻenehana, ka ʻenehana a me ka lāʻau lapaʻau. nā manaʻolana noi.