1,1,1,3,3,3-Hexafluoro-2-propanol CAS:920-66-1

ʻO 1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP) kahi hui like ʻole me nā waiwai kemika ʻokoʻa e hoʻolilo iā ia i mea nui i nā noi ʻoihana like ʻole. Nā Waiwai Hōʻike ʻia ka HFIP e kona ʻano molekala, e hōʻike ana i kahi kalapona tertiary i hoʻopili ʻia i kahi hui hydroxyl (-OH) a hoʻopuni ʻia e ʻeono mau ʻātoma fluorine. Hāʻawi kēia hoʻonohonoho i ke kūpaʻa kūikawā a me ke kiʻekiʻe o ka fluorination, e hāʻawi ana i kona mau waiwai solvent kū hoʻokahi. He wai maopopo ʻole ka HFIP me kahi kiko paila ma kahi o 58 ° C a hōʻike i ka solubility maikaʻi loa i nā solvents polar a me non-polar. ʻO kona hiki ke hoʻopaʻa hydrogen ikaika e lilo ia i mea hoʻoheheʻe maikaʻi no nā hui polar, me nā protein a me nā waikawa nucleic, a hoʻonui i kona pono ma ke ʻano he mea hoʻopaʻa i nā formulations e koi ana i nā wahi inert a me nā wahi non-reactive. Hoʻohana i ka Solvent i ka Organic Synthesis: Hoʻohana nui ʻia ka HFIP ma ke ʻano he solvent i ka kemika organik, ʻoi aku hoʻi no ka hoʻoheheʻe ʻana a me ka hopena o nā hui fluorinated kiʻekiʻe. ʻO kona hiki ke hoʻopaʻa i nā mea waena reactive a hoʻonui i nā helu hopena e lilo ia i mea waiwai nui i ka synthesis o nā lāʻau lapaʻau, agrochemicals, a me nā kemika kūikawā e koi ana i ka mana pololei ma luna o nā kūlana hopena. Kemika Polymer: I ka ʻepekema polymer, lawelawe ʻo HFIP ma ke ʻano he solvent no ka hoʻoheheʻe ʻana a me ka hoʻololi ʻana o nā polymers fluorinated, e like me polytetrafluoroethylene (PTFE) a me polyvinylidene fluoride (PVDF). Hoʻomaʻalahi ia i ka hana ʻana o kēia mau mea i loko o nā kiʻiʻoniʻoni, fibers, a me nā uhi me ka hoʻoikaika ʻana i ka lōʻihi a me ke kū'ē kemika. Nā noi Biomedical: Loaʻa iā HFIP nā noi i ka noiʻi biomedical a me nā ʻano lāʻau lapaʻau ma muli o kona hiki ke hoʻoheheʻe i nā protein a me nā peptides me ka mālama ʻana i ko lākou mau ʻano maoli. Hoʻohana ʻia ia i ka hoʻomākaukau ʻana o nā biomaterials, nā ʻōnaehana lawe lāʻau, a ma ke ʻano he mea hoʻopaʻa i nā lāʻau pale a me nā reagents diagnostic. Hiki ke synthesized ʻia ka Synthesis HFIP e kekahi mau ʻano, me ka hopena o ka hexafluoropropylene me ka wai ma lalo o nā kūlana i kāohi ʻia a i ʻole ka hydrolysis o hexafluoroacetone. ʻO ke ʻano hope e pili ana i ka mālama ʻana i ka hexafluoroacetone me ka wai a me kahi mea hoʻoulu waikawa kūpono e hana i ka HFIP ma ke ʻano he huahana nui. Hoʻohana ʻia nā ʻano hana hoʻomaʻemaʻe e like me ka distillation a i ʻole ka solvent extraction e loaʻa ai ka HFIP i ka maʻemaʻe kiʻekiʻe e kūpono no nā noi ʻoihana a me nā noi keʻena hoʻokolohua. I ka hōʻuluʻulu manaʻo, ʻo 1,1,1,3,3,3-hexafluoro-2-propanol kahi hui like ʻole me nā noi koʻikoʻi i ka synthesis organik, kemika polymer, a me ka noiʻi biomedical. ʻO kona mau waiwai kemika kū hoʻokahi, me ka fluorination kiʻekiʻe, ka hiki ke hoʻopaʻa hydrogen ikaika, a me ka pono o ka solvent, e hiki ai ke hoʻohana nui ʻia ma nā ʻāpana ʻoihana like ʻole, e hāʻawi ana i ka holomua i ka ʻepekema mea, nā lāʻau lapaʻau, a me nā ʻenehana kemika.