1,7-Dimethylindolin-2-one CAS:67358-21-8

He kuleana koʻikoʻi ko 1,7-Dimethylindolin-2-one ma ke ʻano he waena i ka synthesis o nā hui paʻakikī, bioactive me nā noi lāʻau lapaʻau hiki. ʻO kona hoʻokomo ʻia ʻana i loko o nā ʻōnaehana molekala e hiki ai i nā mea noiʻi ke ʻimi i nā moho lāʻau lapaʻau hou e kuhikuhi ana i nā wahi therapeutic e like me nā maʻi ʻōnaehana nerve waena, nā mea antimicrobial, a i ʻole nā ​​​​​​noi kemika mea. ʻO ke alo o ka indolinone core e hoʻolauna i ka reactivity kikoʻī a me nā waiwai pharmacophoric, e lilo ia i mea waiwai no ka noiʻi kemika lāʻau lapaʻau. I nā hana ʻike lāʻau lapaʻau, hiki i kēia hui ke lawelawe ma ke ʻano he kumu hoʻomaka no ka hoʻolālā ʻana i nā moho lāʻau lapaʻau hiki, e hoʻohana ana i kona mau hiʻohiʻona kūkulu e hoʻololi i ka hana olaola a me nā waiwai pharmacokinetic. Eia kekahi, hāʻawi ka ʻano kū hoʻokahi o ka mole i nā manawa kūpono no ka diversification, hiki ke alakaʻi i ka hoʻomohala ʻana o nā molekala hou me nā waiwai olaola i hoʻonui ʻia a me nā ʻano pharmacokinetic i hoʻomaikaʻi ʻia. Eia kekahi, ma nā wahi hoʻonaʻauao a me nā ʻoihana, hiki i nā mea noiʻi ke hoʻohana i kēia poloka hale e hoʻomākaukau i nā hale waihona puke o nā derivatives like ʻole no nā haʻawina pilina hana-hana, e hoʻomaʻamaʻa ana i ka ʻike ʻana i nā hui alakaʻi me nā hopena olaola i makemake ʻia. ʻO kona kuleana i ka synthesis kemika e hoʻonui i ka hana ʻana o nā waena lāʻau lapaʻau a me ka hoʻomohala ʻana i nā ʻano hana synthetic hou, e hōʻike ana i kona pono ākea ma waena o nā aʻo ʻepekema. Ma keʻano holoʻokoʻa, he kuleana koʻikoʻi ko 1,7-Dimethylindolin-2-one i ka ʻimi ʻana i ka ʻike lāʻau lapaʻau hou a me ka noiʻi kemika, e hāʻawi ana i kahi kahua no ka hoʻomohala ʻana i nā molekala biologically active like ʻole a me nā mea lapaʻau waena.