ʻAkika (1S,2S)-2-(3-bromophenyl)cyclopropanecarboxylic CAS:2165565-11-5

Loaʻa i ka waikawa (1S,2S)-2-(3-bromophenyl)cyclopropanecarboxylic ka manaʻolana i ka kemika lāʻau lapaʻau ma ke ʻano he scaffold no ka hoʻomohala ʻana i nā moho lāʻau lapaʻau hiki ke kuhikuhi i nā pahuhopu molekala kikoʻī a i ʻole nā ​​ala maʻi. Hiki i nā mea noiʻi ke ʻimi i kona mau waiwai pharmacological ma ka loiloi ʻana i kona maʻemaʻe enantiomeric a me ke aʻo ʻana i kāna mau pilina me nā ʻōnaehana olaola e loiloi i kona hiki ke therapeutic. Hiki ke hoʻohana ʻia ke ʻano chiral o ka hui e hoʻolālā i nā mea lāʻau lapaʻau koho me ka hoʻomaikaʻi ʻana i ka pono a me nā hopena ʻaoʻao i hoʻemi ʻia. I ka synthesis organik, hiki i kēia hui ke lawelawe ma ke ʻano he kikowaena koʻikoʻi no ke komo ʻana i nā molekala like ʻole ma o nā hoʻololi asymmetric a i ʻole nā ​​​​​​reaction derivatization. ʻO kona hoʻokomo ʻana i loko o nā ala synthetic e ʻae ai i ke kūkulu ʻana i nā ʻōnaehana molekala paʻakikī no ke aʻo ʻana i nā pilina hana-hana a i ʻole ka hoʻolālā ʻana i nā mea kemika hou me nā waiwai i hana ʻia. Ma ka hoʻohana ʻana i kāna stereochemistry a me ka reactivity, hiki i nā mea noiʻi ke hoʻolaha i nā ʻano hana synthetic a hāʻawi i ka hoʻomohala ʻana i nā hui hou no nā noi ʻepekema a me nā ʻoihana like ʻole. Ma keʻano holoʻokoʻa, hōʻike ka waikawa (1S,2S)-2-(3-bromophenyl)cyclopropanecarboxylic i ka maʻalahi a me ka hiki ke hoʻolaha i nā hana ʻimi lāʻau lapaʻau, nā hana synthesis organik, a me ka hana hou kemika, e hōʻike ana i kona koʻikoʻi i ka hoʻolaha ʻana i ka ʻike ʻepekema a me nā holomua lāʻau lapaʻau.