(3R,4S,5R,6R)-3,4,5-tris(triMethylsilyloxy)-6-((triMethylsilyloxy)Methyl)tetrahydro-2H-pyran-2-one CAS:32384-65-9

Hoʻohui ʻia ma o nā ʻano kemika organik, (3R,4S,5R,6R)-3,4,5-tris(trimethylsilyloxy)-6-((trimethylsilyloxy)methyl)tetrahydro-2H-pyran-2-one e hōʻike ana i nā ʻano kūkulu kūikawā koʻikoʻi no kāna mau noi like ʻole. ʻO ke apo tetrahydropyran, me nā hui trimethylsilyloxy, e hoʻohuli i kāna ʻano kemika a me nā pilina hiki me nā molekala ʻē aʻe. Nā noi ma nā lāʻau lapaʻau Hōʻike kēia hui i ka hoʻohiki i ka noiʻi lāʻau lapaʻau ma muli o kāna mau motif kūkulu. Ua ʻike ʻia nā derivatives Pyranone no kā lākou mau hana pharmacological like ʻole, e like me antiviral, antifungal, a me nā waiwai anticancer. ʻO ke alo o nā hui trimethylsilyloxy he nui hiki ke hoʻololi i kona solubility, kūpaʻa, a me ka bioavailability, e hoʻopilikia ana i kona hiki ke therapeutic. Hana Ola a me nā ʻano Hana Hōʻike ka noiʻi e hiki i nā derivatives pyranone ke launa pū me nā ʻōnaehana olaola ma muli o ko lākou ʻano like me nā hui kūlohelohe. Hiki i nā hui trimethylsilyloxy ke hāʻawi i nā waiwai pharmacological kikoʻī, e hoʻohuli paha i kona ʻano hana a me nā ala metabolic. He mea nui ka hoʻomaopopo ʻana i kēia mau ʻano hana no ka hoʻonui ʻana i kona mau hopena therapeutic. Nā Ala Hana a me ka Hoʻomohala ʻana ʻO ka hana ʻana o (3R,4S,5R,6R)-3,4,5-tris(trimethylsilyloxy)-6-((trimethylsilyloxy)methyl)tetrahydro-2H-pyran-2-one e pili ana i nā kaʻina hana organik paʻakikī e hoʻomaka ana mai nā mea hoʻomaka i loaʻa i ke kālepa. He mea koʻikoʻi ka hoʻoponopono maikaʻi ʻana i nā ala hana synthetic no ka hoʻokō ʻana i ka maʻemaʻe kiʻekiʻe, nā hua, a me ka scalability e pono ai no ka hana ʻana ma ka pae ʻoihana a me nā noi lāʻau lapaʻau. Noiʻi o kēia manawa a me nā kuhikuhi e hiki mai ana Ke manaʻo nei ka noiʻi e hoʻomau nei e ʻimi i nā hana olaola āpau o ka hui, me kona hiki ke lilo i mea antiviral a me kona kuleana i ka lāʻau lapaʻau maʻi kanesa. Hiki i nā haʻawina e hiki mai ana ke kālele i nā hoʻololi kūkulu e hoʻomaikaʻi i kāna ʻano pharmacological a me nā maʻi kikoʻī i ka pahuhopu. Eia kekahi, ke hana ʻia nei nā noiʻi i kona hoʻohana ʻana ma ke ʻano he waena synthetic versatile i ka kemika organik. I ka hopena, ʻo (3R,4S,5R,6R)-3,4,5-tris(trimethylsilyloxy)-6-((trimethylsilyloxy)methyl)tetrahydro-2H-pyran-2-one ke hōʻike nei i kahi hui koʻikoʻi i ka kemika organik a me ka noiʻi lāʻau lapaʻau. ʻO kona mau ʻano kūkulu kūikawā a me nā hana pharmacological hiki ke lilo ia i kumuhana o ka ʻimi ʻepekema a me ka hana hou, e paʻa ana i ka hoʻohiki no nā noi like ʻole i ka lāʻau lapaʻau a me ka ʻepekema mea. ʻO ka hoʻomaopopo ʻana i kona synthesis, nā pilina olaola, a me ka hiki ke therapeutic he mea nui ia no ka hoʻohana ʻana i kona mau pono ma nā ʻano like ʻole.