6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one CAS:43200-81-3

Ua hōʻike ʻo 6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one i nā noi like ʻole i ka noiʻi lāʻau lapaʻau a me ka hoʻomohala ʻana i nā lāʻau. Ke aʻo ʻia nei no kāna mau hana olaola a me nā waiwai therapeutic hiki, me kona kuleana ma ke ʻano he moho lāʻau no nā kūlana e like me ke kanesa, ka mumū, a i ʻole nā ​​​​maʻi o ka ʻōnaehana nerve waena. Eia kekahi, hiki i kēia hui ke loaʻa ka pono ma ke kahua o ka kemika lāʻau lapaʻau no ka hoʻolālā ʻana i nā lāʻau lapaʻau hou e kuhikuhi ana i nā ala molekala kikoʻī a i ʻole nā ​​​​kaʻina hana cellular. Hāʻawi kona ʻano kū hoʻokahi a me nā hui hana i nā manawa kūpono no ka hana ʻana i nā hui pharmacologically active me ka hoʻonui ʻia o ka pono a me nā hopena ʻaoʻao i hoʻemi ʻia. Eia kekahi, hiki ke ʻimi ʻia ʻo 6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one no kona mau waiwai antioxidant a me ka hiki ke lilo i mea neuroprotective i ka mālama ʻana i nā maʻi neurodegenerative, kahi e pāʻani ai ke kaumaha oxidative i kahi kuleana koʻikoʻi i ka holomua o ka maʻi. Ma keʻano holoʻokoʻa, ʻo nā noi hiki ke hana ʻia he nui o 6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one e hōʻike ana i kona koʻikoʻi i ka hoʻolaha ʻana i ka ʻike lāʻau lapaʻau, ke kemika lāʻau lapaʻau, a me ka noiʻi biomedical, e paʻa ana i ka ʻōlelo hoʻohiki no ka hoʻoponopono ʻana i nā pono lapaʻau i hoʻokō ʻole ʻia a me ka hoʻomaikaʻi ʻana i nā hopena o ka mea maʻi.