7H-pyrrolo[2,3-d]pyrimidine CAS:271-70-5

Ua loaʻa i ka 7H-Pyrrolo[2,3-d]pyrimidine ka nānā ʻana i ka kemika lāʻau lapaʻau ma muli o kona hiki ke lilo i scaffold no ka synthesizing i nā hui lāʻau lapaʻau hou. Hōʻike ka noiʻi e hiki i nā derivatives o kēia hui ke hōʻike i nā waiwai antitumor, antiviral, a me anti-inflammatory koʻikoʻi. Ma ka hoʻololi ʻana i kona ʻano, hiki i nā mea noiʻi ke hoʻomaikaʻi i ka hana olaola a me ke koho ʻana o nā hui hopena, e lilo ia i wahi hoʻomaka waiwai no ka ʻike ʻana i ka lāʻau. Ua aʻo ʻia kēia hui a me kāna mau derivatives no ko lākou hiki ke launa pū me nā pahuhopu olaola kikoʻī, me nā enzymes a me nā receptors i pili i nā maʻi like ʻole. No ka laʻana, ke ʻimi ʻia nei nā derivatives 7H-pyrrolo[2,3-d]pyrimidine no nā noi i ka lāʻau lapaʻau maʻi kanesa, kahi e hiki ai iā lākou ke kāohi i ka ulu ʻana o nā cell malignant ma ke kuhikuhi ʻana i nā ala hōʻailona koʻikoʻi. Eia kekahi, hōʻike kekahi mau derivatives i ka hiki ke lilo i mau mea antiviral, e hāʻawi ana i kahi kumu no ka hoʻomohala ʻana i nā lāʻau lapaʻau e kūʻē i nā maʻi viral. Ma waho aʻe o nā hoʻohana lāʻau lapaʻau, hiki i ka 7H-pyrrolo[2,3-d]pyrimidine ke loaʻa nā noi i ka ʻepekema mea. ʻO kona ʻano heterocyclic kūikawā e ʻae ai i ka hoʻokomo ʻana i loko o nā mea uila organik a me nā sensor, kahi e hiki ai ke hoʻonui i ka hana o nā semiconductors organik. Ke kālele nei ka noiʻi ma kēia wahi i ka hoʻohana ʻana i nā waiwai o ka hui e hoʻomohala i nā mea hana hou no nā mea uila. I ka hōʻuluʻulu manaʻo, he hui like ʻole a hoʻohiki ʻo 7H-pyrrolo[2,3-d]pyrimidine me nā noi i ka ʻike ʻana i nā lāʻau lapaʻau a me ka ʻepekema mea. ʻO kona mau hiʻohiʻona hoʻonohonoho kū hoʻokahi e hiki ai ke hoʻomohala i nā molekala biologically active, ʻoiai ʻo kona hiki i nā noi uila e hōʻike ana i kona koʻikoʻi i ka noiʻi a me ka hoʻomohala ʻana ma nā ʻāpana he nui.