8-bromoquinazolin-4(3H)-one CAS:77150-35-7

He mea nui ka pono o ka hui 8-bromoquinazolin-4(3H)-one i ka noiʻi lāʻau lapaʻau a me ka synthesis organik. ʻO kekahi hoʻohana nui ʻana, ʻo ia kona kuleana ma ke ʻano he kikowaena koʻikoʻi i ka hoʻomākaukau ʻana i nā hui biologically active a me nā mea lāʻau lapaʻau. Ma ka hoʻohana ʻana i kona reactivity kū hoʻokahi a me nā hiʻohiʻona hoʻonohonoho, hiki i nā mea noiʻi ke hoʻohana i kēia hui e komo i nā derivatives like ʻole me nā hana pharmacological hiki, e kōkua ana i ka hoʻomohala ʻana i nā lāʻau lapaʻau hou a me nā mea therapeutic. Eia kekahi, lawelawe kēia hui ma ke ʻano he scaffold waiwai nui no ka hoʻolālā a me ka synthesis o nā moho lāʻau lapaʻau hiki ke kuhikuhi i nā ala olaola a i ʻole nā ​​​​​​pilina. Ma o ka derivatization a me nā hoʻololi hoʻonohonoho, hiki i nā mea noiʻi ke ʻimi i ka hopena o kēia mau hoʻololi i nā waiwai pharmacological o ka hui, e hiki ai ke ʻike i nā hui alakaʻi no ka hoʻomohala hou aku. Eia kekahi, hiki i ka 8-bromoquinazolin-4(3H)-one ke loaʻa ka noi i ka hoʻomohala ʻana o nā ligands no nā pahuhopu olaola e like me nā receptors a i ʻole nā ​​​​​​enzymes, e hoʻomaʻamaʻa ana i ke aʻo ʻana i nā kaʻina hana biochemical kikoʻī a me nā pilina. Hoʻonui kēia i kona pono i nā hana ʻike lāʻau lapaʻau a me ka wehewehe ʻana i nā ʻano hana olaola. I ka hopena, ʻo ka maʻalahi o kēia hui e hoʻolilo iā ia i waiwai nui i ka noiʻi lāʻau lapaʻau, e hāʻawi ana i nā hiki no ka hoʻokumu ʻana i nā molekala like ʻole me nā hana therapeutic hiki a me ke kōkua ʻana i ka holomua o ka ʻike lāʻau a me nā hana hoʻomohala.