AC-D-Trp-OH CAS:2280-01-5.

He mea nui ka AC-D-Trp-OH i ka kemika peptide ma ke ʻano he ʻāpana koʻikoʻi no ka synthesis o nā peptides a me nā peptidomimetics. Ma ke ʻano he acetylated D-tryptophan derivative, lawelawe ia ma ke ʻano he waena versatile no ka hoʻolauna ʻana i nā koena chiral kikoʻī i loko o nā kaulahao peptide ma o nā ʻano hana synthesis peptide solid-phase a me solution-phase. Hoʻohana nā kānaka noiʻi a me nā kemika iā AC-D-Trp-OH e hoʻopilikino i nā moʻo peptide me ka mana stereochemical pololei, e hiki ai ke hoʻolālā i nā hui bioactive hou a me nā peptides therapeutic e kuhikuhi ana i nā receptors, enzymes, a i ʻole nā ​​​​mea lawe i nā ʻōnaehana olaola. Eia kekahi, hoʻohana ʻia ʻo AC-D-Trp-OH ma ke ʻano he poloka hale chiral i ka hana ʻana o nā waena lāʻau lapaʻau, kahi e pono ai kona stereochemistry kū hoʻokahi no ka synthesis o nā lāʻau chiral a me nā hui bioactive. ʻO kona chirality a me ke kūpaʻa e lilo ia i mea nui loa i ka hana ʻana i nā huahana lāʻau lapaʻau, e hoʻonui ana i nā waiwai pharmacological a me ka hana olaola o nā moho lāʻau hope loa. Eia kekahi, hoʻohana ʻia ʻo AC-D-Trp-OH i ka noiʻi biochemical e aʻo i ka metabolism tryptophan, ka hana protein, a me ka neurochemistry. ʻO kāna kuleana i ka wehewehe ʻana i nā kuleana o nā molekala i loaʻa mai ka tryptophan i ka neurotransmission, ka hoʻoponopono ʻana i ke ʻano, a me nā mele circadian e kōkua i ka hoʻomaopopo ʻana i ko lākou hopena hiki i nā maʻi neurological a me nā kūlana psychiatric. I ka hōʻuluʻulu manaʻo, he kuleana koʻikoʻi ko AC-D-Trp-OH i ka hoʻolaha ʻana i ka noiʻi ʻepekema, ka hoʻomohala ʻana i nā lāʻau lapaʻau, a me nā haʻawina biochemical, e hāʻawi ana i nā ʻepekema a me nā poʻe loea i kahi mea hana versatile e ʻimi ai i nā noi like ʻole o nā derivatives tryptophan i ka ʻike ʻana i nā lāʻau lapaʻau, ka peptide synthesis, a me nā noiʻi biochemical.