ʻAsamycin CAS:72559-06-9

Hoʻohana pinepine ʻia nā Ansamycins, e like me nā rifamycins, i ka hana lapaʻau e mālama i nā ʻano maʻi bacteria like ʻole, me ka maʻi tuberculosis, ka maʻi lepera, a me kekahi mau ʻano maʻi staphylococcal a me streptococcal. ʻO Rifampin, kahi rifamycin kaulana, hoʻohana pinepine ʻia ma ke ʻano he ʻāpana o ka hui pū ʻana no ka maʻi tuberculosis a me nā maʻi mycobacterial ʻē aʻe. ʻO ke ʻano hana o nā ansamycins e pili ana i ka hoʻopaʻa ʻana i ka bacteria RNA polymerase, a laila e pale ana i ka transcription a i ka hopena e alakaʻi ai i ka make ʻana o nā cell bacteria. ʻO kēia ʻano hana kū hoʻokahi e hoʻoikaika ai i nā ansamycins e kūʻē i kahi ākea o nā bacteria Gram-positive a me Gram-negative. Noʻonoʻo pono nā mea mālama ola i nā mea e like me ke ʻano o ka maʻi, ka mōʻaukala olakino o ka mea maʻi, a me nā hopena hoʻāʻo susceptibility bacteria i ke kuhikuhi ʻana i nā ansamycins. ʻO ka dosing kūpono, ka lōʻihi o ka mālama ʻana, a me ka nānā ʻana no nā hopena ʻaoʻao hiki ke hoʻonui i nā pono therapeutic me ka hoʻemi ʻana i nā pilikia e pili ana i ka hoʻohana ʻana i ka antibiotic. ʻO nā hopena maikaʻi ʻole e pili ana i nā ansamycins e komo pū me nā haunaele gastrointestinal, hepatotoxicity, a me nā hopena hypersensitivity. ʻO ka nānā mau ʻana i nā hoʻokolohua hana ate a me ka nānā pono ʻana no kekahi mau hōʻailona o nā hopena maikaʻi ʻole e kōkua i ka hōʻoia ʻana i ka hoʻohana palekana a me ka maikaʻi o nā ansamycins i ka mālama ʻana i nā maʻi bacteria. Ma keʻano holoʻokoʻa, hōʻike nā ansamycin i kahi papa waiwai o nā antibiotics me nā noi like ʻole i ka mālama ʻana i nā maʻi bacteria. Ma o ka hoʻohana kūpono a me ka nānā ʻana, hiki i nā loea mālama ola ke hoʻohana i nā waiwai antimicrobial o nā ansamycins e hakakā pono i nā maʻi a hoʻomaikaʻi i nā hopena o ka mea maʻi.