ʻO ka Arecoline hydrobromide CAS: 300-08-3

ʻO nā hopena pharmacological o Arecoline hydrobromide e komo pū me ka hoʻoulu ʻana i ka ʻōnaehana nerve parasympathetic a me ka hoʻonui ʻana i ka neurotransmission cholinergic. ʻOiai ua hoʻohana ʻia ma ka lāʻau lapaʻau kuʻuna no kona mau hopena hoʻoulu, ua noiʻi pinepine ʻia no kāna kuleana i nā haʻawina neuroscience e pili ana i nā mea loaʻa acetylcholine a me nā ala hōʻailona neuronal. I ka noiʻi lapaʻau, hoʻohana ʻia ka arecoline hydrobromide ma ke ʻano he mea hana noiʻi e aʻo ai i ka hana receptor acetylcholine, ka hoʻonāukiuki neuronal, a me nā ʻano hana hoʻokuʻu neurotransmitter. ʻO kona mau waiwai cholinergic e lilo ia i mea waiwai i ka wehewehe ʻana i nā pilina paʻakikī i loko o ka ʻōnaehana nerve a me nā pahuhopu therapeutic hiki no nā kūlana neurological. ʻOiai kona pono noiʻi, ua kaupalena ʻia ka hoʻohana lapaʻau o ka arecoline hydrobromide ma muli o kona mau hopena ʻaoʻao, me nā haunaele gastrointestinal, diaphoresis, a me nā hopena cardiovascular. Eia kekahi, ʻo kona pilina me ka nau ʻana i ka betel nut a me ka carcinogenicity e hoʻāla i nā hopohopo e pili ana i ka palekana lōʻihi a me nā hopena olakino. Ma keʻano holoʻokoʻa, ʻoiai ʻo ka arecoline hydrobromide e hōʻike ana i ka hoʻohiki ma nā wahi noiʻi no ke aʻo ʻana i ka hana neuronal a me nā ala cholinergic, ua kaupalena ʻia kāna mau noi lapaʻau e nā noʻonoʻo palekana a me nā hopena maikaʻi ʻole. ʻO ka hoʻomau ʻana o ka noiʻi ʻana i kona mau waiwai pharmacological e hāʻawi i ka ʻike i nā lāʻau lapaʻau hou e pili ana i nā ʻōnaehana cholinergic akā pono e loiloi pono i nā pilikia a me nā pono no ka hoʻohana therapeutic kūpono.