ʻO Boc-Asp(OBzl)-OSu CAS:13798-75-9

Hoʻohana nui ʻia ʻo Boc-Asp(OBzl)-OSu i ka peptide synthesis ma ke ʻano he reagent coupling no ka hoʻokomo koho ʻana o ka waikawa L-aspartic i loko o nā kaulahao peptide. Ma ke ʻano he derivative ester N-hydroxysuccinimide (NHS), hoʻomaʻamaʻa ia i ka hoʻokumu ʻana o nā pilina amide paʻa ma waena o ka hui carboxyl o Boc-Asp(OBzl) a me nā hui amino o nā molekala ʻē aʻe, e hiki ai ke hōʻuluʻulu peptide pololei a kāohi ʻia. He mea koʻikoʻi kēia no ka ʻike ʻana a me ka hoʻomohala ʻana i nā lāʻau lapaʻau, a no nā haʻawina biochemical e pili ana i ka hoʻomaopopo ʻana i nā pilina protein a me nā ala hōʻailona. Eia kekahi, he kuleana koʻikoʻi ʻo Boc-Asp(OBzl)-OSu i ka hoʻololi kikoʻī o nā protein a me nā peptides no nā noiʻi like ʻole a me nā noi therapeutic. ʻO kona maʻemaʻe kiʻekiʻe a me kona ʻano kūlike e hōʻoia i ka hilinaʻi a me ka hana hou ʻana i nā kaʻina hana noiʻi, e lilo ia i mea hana waiwai no nā ʻepekema a me nā mea noiʻi ma nā ʻano like ʻole, mai ka noiʻi kumu a hiki i ka hoʻomohala ʻana i nā lāʻau lapaʻau hou a me nā hui bioactive. I ka hōʻuluʻulu manaʻo, he mea nui ʻo Boc-Asp(OBzl)-OSu i ka hoʻolaha ʻana i nā ʻike ʻepekema a me nā lāʻau lapaʻau ma o ka hiki ʻana ke hana ʻia nā peptides paʻakikī me nā waiwai i hana kūikawā ʻia, e kākoʻo ana i ka hoʻomohala ʻana i nā lāʻau lapaʻau hou a me nā mea lapaʻau. ʻO kona ʻano maʻalahi a me ka hoʻohana nui ʻia ʻana i ka noiʻi lāʻau lapaʻau e hōʻike ana i kona koʻikoʻi ma ke ʻano he mea hana waiwai no nā kānaka ʻepekema a me nā mea noiʻi ma ka honua holoʻokoʻa.