ʻO Boc-Trp-OSu CAS:3392-11-8

He mea nui ʻo Boc-Trp-OSu i ke kemika bioconjugation, ʻoi aku hoʻi i ka hana ʻana o nā peptides a me nā protein no nā noi i kuhikuhi ʻia. Ma ke ʻano he derivative NHS ester, hoʻomaʻamaʻa ia i ka hoʻopili covalent o ka ʻāpana tryptophan i pale ʻia e Boc me nā amines mua i loaʻa i nā waikawa amino, peptides, a i ʻole nā ​​​​protein. ʻAe kēia conjugation koho no ka hoʻololi pololei ʻana o nā koena waikawa amino kikoʻī i loko o kahi moʻo peptide a i ʻole ka N-terminus o kahi protein, e hiki ai ke hoʻolauna i nā hui hana a i ʻole nā ​​​​lepili no nā kumu like ʻole. Hoʻohana nā kānaka noiʻi a me nā biochemists iā Boc-Trp-OSu i ka hoʻomohala ʻana o nā peptide conjugates no nā noi e like me ka lawe ʻana i nā lāʻau lapaʻau i kuhikuhi ʻia, immunoassays, a me ka hana biomaterial. Ma ka hoʻopili ʻana i nā peptides i hoʻololi ʻia e Boc-Trp-OSu i nā molekala a i ʻole nā ​​​​​​ʻili i kuhikuhi ʻia, hiki iā lākou ke hana i nā mea hana bioactive i hiki ke launa pū me nā mea loaʻa cellular, antigens, a i ʻole nā ​​​​​​matrices biological. Eia kekahi, loaʻa iā Boc-Trp-OSu ka hoʻohana ʻana i ka hoʻomākaukau ʻana o nā peptide-protein conjugates no ka hana ʻana i nā antibody-drug conjugates (ADCs) a me ka lepili protein no nā kiʻi a me nā diagnostic assays. ʻO ka versatility o Boc-Trp-OSu e lilo ia i mea hana pono ʻole ma nā ʻano like ʻole e like me ke kemika biology, biotechnology, a me nā ʻepekema lāʻau lapaʻau. ʻO kona kūlike me nā protocols bioconjugation, ka reactivity kiʻekiʻe, a me ke koho ʻana e kōkua i kona hoʻohana ākea ʻana i nā wahi hoʻonaʻauao a me nā ʻoihana. Inā hoʻohana ʻia i ka noiʻi kumu a i ʻole ka hoʻomohala ʻana i nā therapeutics holomua, hiki iā Boc-Trp-OSu ke hana i nā peptide conjugates i hana kūikawā ʻia he mea nui i ka hoʻolaha ʻana i nā therapies i kuhikuhi ʻia a me nā diagnostics molecular.