ʻO Capastat sulfate (Capreomycin sulfate) CAS: 1405-37-4

He kuleana koʻikoʻi ko Capastat sulfate (Capreomycin sulfate) i ka mālama ʻana i ka maʻi tuberculosis multidrug-resistant, kahi ʻano maʻi tuberculosis i kū i nā lāʻau lapaʻau anti-TB laina mua. Hoʻohana pinepine ʻia ia me nā lāʻau lapaʻau laina lua ʻē aʻe e kuhikuhi pono a mālama i nā maʻi MDR-TB. Ma muli o kāna hana bactericidal e kūʻē i nā ʻano Mycobacterium tuberculosis i kū i nā lāʻau lapaʻau laina mua e like me isoniazid a me rifampin, ua mālama ʻia ʻo Capastat sulfate no nā hihia kahi i kūleʻa ʻole ai nā lāʻau lapaʻau TB maʻamau. Hoʻokele pinepine ʻia ka mālama ʻana me Capastat sulfate ma lalo o ka nānā ʻana o nā loea olakino i ʻike i ka mālama ʻana i ka maʻi tuberculosis kū i ka lāʻau. Hoʻopilikino ʻia ka nui a me ka lōʻihi o ka lāʻau lapaʻau Capastat sulfate i nā pono o kēlā me kēia mea maʻi e pili ana i nā mea e like me ke koʻikoʻi o ka maʻi, ke kaumaha o ka mea maʻi, a me ka hana renal. He mea nui ka nānā mau ʻana i ka hana renal a me ka lohe i ka wā o ka mālama ʻana, no ka mea, hiki i nā antibiotics aminoglycoside e like me Capreomycin ke hōʻino i ka renal a me ka nalowale o ka lohe. Pono nā mea maʻi e hana ana i ka lāʻau lapaʻau Capastat sulfate e hahai pono i kā lākou regimen lapaʻau i kuhikuhi ʻia e hoʻokō i nā hopena maikaʻi loa a hoʻemi i ka pilikia o ka hoʻomohala ʻana i ke kūʻē hou aʻe. He mea nui ka mālama pono ʻana i ke kaʻina hana piha e hōʻoia i ka hoʻopau piha ʻana o ka MDR-TB a hōʻemi i ka hiki ke kūleʻa ʻole ka lāʻau a i ʻole ka hoʻi hou ʻana. Paipai ʻia ka nānā pono ʻana no nā hopena maikaʻi ʻole a me nā loiloi hahai mau me nā mea mālama ola e hoʻokele i nā hopena ʻaoʻao a hoʻonui i nā pono therapeutic o Capastat sulfate i ka hakakā ʻana i ka maʻi puʻupuʻu kūʻē i ka lāʻau.