ʻO Colistin sodium methanesulfonate mai ka bacillus colistinus CAS: 8068-28-8

Hoʻohana nui ʻia ʻo Colistin sodium methanesulfonate i ka mālama ʻana i nā maʻi bacteria koʻikoʻi i hoʻokumu ʻia e nā bacteria gram-negative, ʻoiai nā ʻano i kū i nā papa antibiotic he nui. Hoʻohana pinepine ʻia ia i nā hihia o ka pneumonia i loaʻa i ka haukapila, ka pneumonia e pili ana i ka ventilator, sepsis, a me nā maʻi urinary tract i ka wā i hoʻokumu ʻia e nā pathogens multidrug-resistant e like me Pseudomonas aeruginosa, Acinetobacter baumannii, a me Klebsiella pneumoniae. He mea nui ka dosing kūpono a me ka hoʻokele ʻana o colistin sodium methanesulfonate no ka hoʻokō ʻana i nā hopena therapeutic maikaʻi loa. Ma muli o kona hiki ke nephrotoxicity a me neurotoxicity, pono ka nānā pono ʻana i ka hana renal a me ke kūlana neurological i ka wā o ka mālama ʻana. Pono paha nā hoʻoponopono dosage ma muli o ka hana renal a me nā mea maʻi pākahi. Ma mua o ka hoʻohana ʻana i ka colistin sodium methanesulfonate, pono nā mea lawelawe olakino e loiloi i ka hiki ʻole o ka meaola maʻi e hōʻoia i ka lāʻau kūpono. Hiki i nā hopena maikaʻi ʻole ke komo pū me ka hōʻino ʻana o ka renal, nā pilikia hanu, a me nā hopena allergic, e pono ai ka nānā makaʻala i ka wā o ka mālama ʻana. I ka hōʻuluʻulu manaʻo, he lāʻau antibiotic koʻikoʻi ka colistin sodium methanesulfonate no ka hakakā ʻana i nā maʻi gram-negative multidrug-resistant a pono e mālama ʻia no nā kūlana kahi i loaʻa ʻole ai nā koho ʻē aʻe. ʻO kona hoʻohana akamai ʻana, i alakaʻi ʻia e nā loina mālama antimicrobial, he mea nui ia e mālama i kona pono a pale i ka puka ʻana mai o nā ʻano kū'ē hou aʻe.