Cytochalasin B CAS:14930-96-2 Kumukūʻai Mea Hana

He hui kūlohelohe ʻo Cytochalasin B i loaʻa mai nā ʻano fungi like ʻole. No loko ia o kahi papa o nā hui i ʻike ʻia he cytochalasins, i ʻike ʻia no ka hoʻopilikia ʻana i ka cytoskeleton o nā cell.

ʻO ka hopena nui o ka cytochalasin B ka pale ʻana i ka polymerization actin. He protein ʻo Actin e pāʻani ana i kahi kuleana koʻikoʻi i ka mālama ʻana i ke ʻano a me ka neʻe ʻana o ke kelepona. Ma ka hoʻopilikia ʻana me ka actin, hoʻopilikia ka cytochalasin B i nā kaʻina hana kelepona like ʻole.

ʻO kekahi o nā hoʻohana nui o ka cytochalasin B ʻo ia ka noiʻi biology cell. Hoʻohana pinepine ʻia ia ma ke ʻano he mea hana e aʻo ai i ka dynamics actin a me kāna kuleana i nā kaʻina hana cellular like ʻole, e like me ka mahele cell, ka neʻe ʻana o ke cell, a me ka endocytosis. Ma ka pale ʻana i ka polymerization actin, hiki i ka cytochalasin B ke noiʻi i ka hana a me ke koʻikoʻi o ka actin i kēia mau kaʻina hana.

Eia kekahi, ua hōʻike ʻo cytochalasin B i nā noi therapeutic hiki. Ua aʻo ʻia no kona hiki ke kāohi i ka ulu ʻana o kekahi mau ʻano cell cancer, e hōʻike ana i kona hiki ke lilo i mea anticancer. Eia kekahi, ua hōʻike ʻo ia i ka hana antiviral e kūʻē i kekahi mau virus, e hōʻike ana i kona hiki ke hoʻohana ʻia i nā therapies antiviral.