Duloxetine HCL CAS:136434-34-9 Mea Hana Mea Hoʻolako

ʻO Duloxetine HCL ke ʻano paʻakai o ka lāʻau antidepressant duloxetine. Ua hoʻomohala pono ʻia e Eli Lilly Company. ʻO kona hopena pharmacological ua like ia me ka duloxetine. ʻO Duloxetine hydrochloride kahi ʻano hou o ka mea hoʻopaʻa pālua koho o 5 hydroxy trptamine (5-HT) a me ka norepinephrine reuptake, a no laila he hopena antidepressant, ʻoiai he hopena inhibitory ma ke kikowaena ʻeha. ʻO kona ʻano pharmacological ka hiki ke kāohi i ka neuronal pre-synaptic membrane reuptake ma 5-hydroxy trptamine a me norepinephrine akā he hopena inhibitory haʻahaʻa ma ka reuptake o dopamine. Hōʻike ʻia ʻo Duloxetine hydrochloride no ke kaumaha a he pono ia i ka mālama ʻana i nā kaumaha endogenous a me non-endogenous a me ka manaʻo o ka ʻeha e pili ana me ke kaumaha. Loaʻa iā ia kahi mahele therapeutic o 60mg/d ~ 120mg/d me ka palekana maikaʻi a me nā hopena maikaʻi ʻole me nā hopena maikaʻi ʻole maʻamau e like me ka nausea, ka waha maloʻo, ka constipation, ka makemake ʻole, ka luhi, ka hiamoe, a me ka hoʻonui ʻana i ka hou. ʻO kekahi hōʻailona ʻo ia ka ʻeha i hoʻokumu ʻia e ka neuropathy diabetic.