ʻETHYL 2-METHYL-4,4,4-TRIFLUOROACETOACETATE CAS:344-00-3

ʻIke ʻia ʻo N-Ethyl 2-methyl-4,4,4-trifluoroacetoacetate (EMTFA) e kona ʻano molekala, nona kahi hui trifluoromethyl (-CF3) i hoʻopili ʻia i kahi iwi kuamoʻo β-keto ester. Hāʻawi kēia ʻano i ke kūpaʻa koʻikoʻi a me ka reactivity iā EMTFA, e kūpono ai no nā ʻano noi kemika like ʻole. Loaʻa ka EMTFA ma ke ʻano he wai maopopo, kala ʻole me kahi kiko paila ma kahi o 140°C a hōʻike i ka solubility maikaʻi i nā mea hoʻoheheʻe organik maʻamau e like me ka acetone a me ka ethyl acetate. ʻO kona kūpaʻa ma lalo o nā kūlana like ʻole e ʻae ai i kona hoʻohana pono ʻana i nā noiʻi hale hana a me nā kaʻina hana ʻoihana. Hoʻohana Organic Synthesis: Hana ʻo EMTFA ma ke ʻano he poloka hale koʻikoʻi i ka synthesis organik, ʻoi aku hoʻi i ka hoʻolauna ʻana o nā motif trifluoromethylated i loko o nā mole organik. He mea nui kēia hiki no ka hoʻomohala ʻana i nā lāʻau lapaʻau, nā agrochemicals, a me nā kemika kūikawā me ka hana olaola i hoʻonui ʻia a me ke kūpaʻa kemika. Kemika lāʻau lapaʻau: I nā noi lāʻau lapaʻau, hoʻohana ʻia ʻo EMTFA ma ke ʻano he precursor i ka synthesis o nā mea hana lāʻau lapaʻau ikaika (APIs) ma muli o kona hiki ke hāʻawi i nā waiwai pharmacological i makemake ʻia. He kuleana koʻikoʻi kona i ke kemika lāʻau lapaʻau ma o ka hiki ʻana ke hoʻololi i nā molekala lāʻau lapaʻau e hoʻonui i ka pono a hōʻemi i ka hiki ke hoʻololi i ka metabolic. Nā Kemika Kūikawā: Loaʻa ka hoʻohana ʻana o EMTFA i ka hana ʻana o nā kemika kūikawā e like me nā herbicides, insecticides, a me nā mea waena paʻakikī i hoʻohana ʻia i ka synthesis o nā agrochemicals a me nā kemika maikaʻi. ʻO kona versatility i nā hoʻololi kemika e lilo ia i mea waiwai i nā formulations kahi e pono ai ka mana pololei ma luna o ka hoʻonohonoho molekala a me ka hana. Synthesis Ethyl 2-methyl-4,4,4-trifluoroacetoacetate i synthesized ʻia ma o kahi kaʻina hana multistep e hoʻomaka ana me ka hopena condensation Claisen o ka ethyl trifluoroacetate me ka methyl acetate, ukali ʻia e ka esterification ma lalo o nā kūlana i kāohi ʻia. Hoʻomau pinepine ka hopena i ke alo o kahi mea hoʻoulu kumu e hoʻomaʻamaʻa i ka hoʻokumu ʻana o β-keto ester. Hoʻohana ʻia nā ʻano hana hoʻomaʻemaʻe e like me ka distillation a i ʻole recrystallization e loaʻa ai ka EMTFA i ka maʻemaʻe kiʻekiʻe i kūpono no nā noi ʻoihana. ʻO ke ala synthesis pololei a me ka loaʻa ʻana o nā mea hoʻomaka e hāʻawi i kona kumukūʻai kūpono a me ka hoʻohana ākea ʻana i ka noiʻi kula a me nā kaʻina hana ʻoihana. I ka hōʻuluʻulu manaʻo, he hui like ʻole ka ethyl 2-methyl-4,4,4-trifluoroacetoacetate me nā noi koʻikoʻi i ka synthesis organik, kemika lāʻau lapaʻau, a me ka hana ʻana i nā kemika kūikawā. ʻO kona mau waiwai kemika kū hoʻokahi, me ke kūpaʻa, ka reactivity, a me ka maʻalahi o ka synthesis, hoʻonoho iā ia ma ke ʻano he mea nui i ka hoʻolaha ʻana i nā ʻenehana ma nā ʻāpana ʻoihana like ʻole a me nā aʻo ʻepekema.