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2′-O-Methyluridine CAS:2140-76-3 Kumukūʻai Mea Hana
ʻO 2′-O-Methyluridine kahi nucleoside i hoʻololi ʻia nona kahi hui methyl ma ke kūlana 2′ o ke apo ribose. He poloka hale koʻikoʻi ia i ka synthesis o nā molekala RNA i hoʻololi ʻia a ua aʻo ʻia no kona mau waiwai olaola a me nā pharmacological. ʻO kekahi o kāna mau noi i hōʻike ʻia e pili ana i kona hoʻohana ʻana i ka noiʻi RNA, ma ke ʻano he ʻāpana i ka hana ʻana o RNA i hoʻololi ʻia no nā noi genomics therapeutic a me functional, a ma ke ʻano he mea hana i ke aʻo ʻana i ke ʻano a me ka hana RNA.
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4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one CAS:951-77-9
ʻO 2′-Deoxycytidine kahi nucleoside i haku ʻia me ka nucleobase cytosine i pili i ke kō deoxyribose. He ʻāpana koʻikoʻi ia o ka DNA a he kuleana koʻikoʻi kona i ka mālama ʻana a me ka hoʻoili ʻana i ka ʻike genetic i loko o nā meaola ola.
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Cytidine-5′-monophosphate (CMP), waikawa manuahi CAS:63-37-6
ʻO Cytidine 5'-monophosphate (CMP) kahi nucleotide e lawelawe ana ma ke ʻano he poloka kūkulu no ka synthesis a me ka hoʻololi ʻana o RNA. He ʻāpana koʻikoʻi ia i ke kūkulu ʻana o nā molekala RNA a pili i nā kaʻina hana e like me ka mRNA capping a me ka metabolism nucleotide. Hoʻohana ʻia ʻo CMP i ka noiʻi biochemical a me ka molecular biology no nā noi e like me ka in vitro transcription a me ka nucleic acid labeling. ʻO kona kuleana i ka metabolism RNA a me kona hoʻohana ʻana i nā ʻano hana hoʻokolohua like ʻole e lilo ia i mea hana koʻikoʻi i ka hoʻomaopopo ʻana i ke ʻano a me ka hana o nā molekala RNA.
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IBMX, 3-isobutyl-1-methylxanthine CAS:28822-58-4
ʻO 3-isobutyl-1-methylxanthine, i ʻike ʻia hoʻi ʻo IBMX, he methylxanthine derivative i hoʻohana pinepine ʻia i ka noiʻi ʻepekema ma ke ʻano he mea hoʻopale ʻole kikoʻī o nā cyclic nucleotide phosphodiesterases. Ua ʻike ʻia e hoʻonui i nā pae intracellular o cyclic AMP (cAMP) a me cyclic GMP (cGMP) ma ke kāohi ʻana i ko lākou haki ʻana, hiki ke hoʻololi i nā ala hōʻailona cellular like ʻole.
Ma waho aʻe o kāna mau noiʻi noiʻi, ua hoʻohana ʻia ʻo IBMX ma kekahi mau wahi lapaʻau no kona hopena bronchodilator a me vasodilator. Eia nō naʻe, ua kaupalena ʻia kona hoʻohana ʻana i ka lāʻau lapaʻau kanaka.
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4-Nitrophenyl phosphate disodium paʻakai hexahydrate CAS: 4264-83-9
ʻO 4-Nitrophenyl phosphate disodium salt hexahydrate kahi hui kemika i hoʻohana pinepine ʻia i ka noiʻi biochemical a me nā lāʻau lapaʻau. He ʻano paʻakai ia o 4-nitrophenyl phosphate, nona ʻelua mau ion sodium a me ʻeono mau molekala wai. Hoʻohana pinepine ʻia kēia hui ma ke ʻano he substrate no nā hoʻāʻo phosphatase a me ke aʻo ʻana i nā kinetics enzyme.
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5′-Deoxy-5-fluorocytidine CAS:66335-38-4
ʻO 5′-Deoxy-5-fluorocytidine kahi analog nucleoside synthetic e noiʻi ʻia nei no kāna hana antiviral hiki, ʻoi aku hoʻi i nā virus RNA e like me ka maʻi hepatitis C (HCV) a me nā flaviviruses. Hana ia ma ke keakea ʻana i ka hana hou ʻana o ka mea genetic viral, a laila pale i ka hiki o ka virus ke hoʻonui a hoʻolaha i loko o ke kino.
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ʻO Cytidine-5′-triphosphate (CTP), paʻakai disodium CAS: 652154-13-7
ʻO Cytidine-5′-triphosphate (CTP), ka paʻakai disodium he nucleoside triphosphate e lawelawe ana ma ke ʻano he poloka kūkulu no ka synthesis RNA. He kuleana koʻikoʻi kona i ka metabolism cellular a he mea nui ia no ka hoʻoili ʻana o ka ʻike genetic mai DNA a i RNA i ka wā o ka transcription. Hoʻohana nui ʻia ʻo CTP i ka noiʻi biology molecular, ʻoi aku hoʻi i nā haʻawina e pili ana i ka synthesis RNA, ka hoʻopilikia RNA, a me nā kaʻina hana ʻē aʻe e pili ana i ka RNA. Eia kekahi, hoʻohana ʻia ia i nā hopena enzymatic, nā haʻawina metabolism nucleotide, a ma ke ʻano he substrate no nā hoʻāʻo biochemical like ʻole. I ka ʻoihana lāʻau lapaʻau, hiki i ka CTP ke loaʻa nā noi kūpono i ka hoʻomohala ʻana i nā lāʻau antiviral a me nā anticancer.
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ITP, inosine 5′-triphosphate trisodium paʻakai CAS:35908-31-7
ʻO ka paʻakai Inosine-5′-triphosphate trisodium, i hoʻopōkole pinepine ʻia ʻo ITP-Na3, he ʻano triphosphate o ka inosine, kahi nucleoside e pāʻani ana i kahi hana koʻikoʻi i nā kaʻina hana olaola like ʻole. He ʻano paʻakai kēia hui, e hoʻolilo ana iā ia i mea hoʻoheheʻe wai a kūpono no ka hoʻohana ʻana i nā hoʻāʻo biochemical a me enzymatic, a me ka noiʻi biology molecular. Hoʻohana ʻia ka paʻakai Inosine-5′-triphosphate trisodium no ke aʻo ʻana i nā hopena enzymatic, ka interconversion nucleotide, a ma ke ʻano he substrate no kekahi mau enzymes. Hoʻonui pū ʻia kāna mau noi i nā haʻawina analog nucleotide a ma ke ʻano he ʻāpana i ka hoʻomākaukau ʻana i nā hui nucleotide i hoʻohana ʻia i nā ʻenehana biology molecular.
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5-Bromouracil CAS:51-20-7 Kumukūʻai Mea Hana
He analog synthetic ʻo 5-Bromouracil o ka uracil, ʻo ia kekahi ʻāpana o ka RNA. Hiki ke hoʻokomo ʻia ʻo 5-Bromouracil i loko o nā waikawa nucleic a hiki ke hoʻoulu i nā mutations ma o ka mispairing me ka guanine i ka wā o ka hana hou ʻana o ka DNA. Hoʻohana ʻia ia ma ke ʻano he mutagen i ka noiʻi genetic e aʻo i nā helu mutation a me nā ʻano hana.
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5-Fluoro-2′-deoxyuridine CAS:50-91-9
ʻO 5-Fluoro-2′-deoxyuridine kahi analog nucleoside synthetic e kāohi ana i ka synthesis DNA. Ua aʻo ʻia no kona mau waiwai antiviral a me antitumor. Eia kekahi, hoʻohana ʻia ia ma ke ʻano he mea hana noiʻi i ka biology molecular a me ka biochemistry.
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Paʻakai disodium Cytidine-5′-triphosphate CAS:36051-68-0
ʻO ka paʻakai disodium Cytidine-5′-triphosphate (CTP-Na2) he nucleoside triphosphate e lawelawe ana ma ke ʻano he poloka kūkulu i ka synthesis o RNA. He kuleana koʻikoʻi kona i ka metabolism cellular, e lawelawe ana ma ke ʻano he substrate no nā RNA polymerases i ka transcription a ma ke ʻano he kumu ikehu no nā ʻano hana enzymatic like ʻole. Hoʻohana pinepine ʻia ʻo CTP-Na2 i ka noiʻi biochemical a me ka molecular biology ma ke ʻano he ʻāpana i nā hopena e pili ana i ka synthesis RNA, ka hoʻololi ʻana, a me ka hoʻoponopono ʻana. Hoʻonui kona ʻano paʻakai disodium i kona solubility i nā hopena wai, e ʻoi aku ka maʻalahi no ka hoʻohana ʻana i ka hale hana.
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ʻO ka waikawa Ribonucleic mai ka mea hū a Baker CAS: 63231-63-0
ʻO ka waikawa Ribonucleic (RNA) mai ka hū a Baker, i ʻike ʻia hoʻi ʻo Saccharomyces cerevisiae, e pili ana i nā molekala RNA i loaʻa i loko o kēia fungi cell hoʻokahi maʻamau. Hana ia i nā hana koʻikoʻi like ʻole i loko o ke kelepona, me ka synthesis protein, ka hana enzymatic, a me ka hoʻoponopono ʻana i nā gene. He mea hoihoi ka RNA mai ka hū a Baker i nā kānaka ʻepekema a me nā mea noiʻi e aʻo ana i ka biology molecular, genetics, a me nā kaʻina hana cellular. Hoʻohana ʻia ia i nā ʻano hoʻokolohua a me nā haʻawina e loaʻa ai ka ʻike i ka hōʻike ʻana o ka gene, ka hana RNA, a me nā ʻano molekala e pili ana i nā hana cellular.
