ʻO Fmoc-Arg(Tos)-OH CAS:83792-47-6

He kuleana koʻikoʻi ko Fmoc-Arg(Tos)-OH i ka synthesis peptide, ʻoiai ke koi ʻia ka pale pololei o ka guanidine nitrogen i loko o ka arginine. Pale ka hui pale Fmoc i ka hui amino, e hōʻoiaʻiʻo ana i nā hopena koho i ka wā o ka hoʻopili ʻana o ka peptide, ʻoiai ʻo ka hui tosyl ma ka guanidine nitrogen e hāʻawi i kahi papa pale hou aʻe. Hoʻohana nā kānaka noiʻi iā Fmoc-Arg(Tos)-OH no ka synthesizing peptides me nā hoʻololi guanidine kikoʻī, e hoʻohuli ana i kā lākou hana olaola. ʻO ke ʻano pale pālua e hiki ai ke hoʻoponopono i ka hana guanidine i kāohi ʻia, e lilo ai kēia hui i mea waiwai nui i ka hoʻolālā ʻana i nā peptides no nā haʻawina antimicrobial, bioconjugation, a me ka kemika lāʻau lapaʻau. ʻO ka kūlike o Fmoc-Arg(Tos)-OH me nā ʻano hana synthesis peptide maʻamau, me ka synthesis peptide solid-phase (SPPS), e hoʻonui i kona pono. Loaʻa i kēia hui ka noi i ke kūkulu ʻana i nā peptides no nā assays olaola, ka ʻike lāʻau, a me ka hoʻomohala ʻana i nā mea peptide-based. ʻO ka wehe ʻana i nā hui pale i kāohi ʻia e ʻae i ka hoʻohui hoʻolālā o ka arginine me ka guanidine i hoʻololi ʻia, e hāʻawi ana i ka ʻokoʻa o nā peptides hiki ke synthesized. I ka hōʻuluʻulu manaʻo, kū ʻo Fmoc-Arg(Tos)-OH ma ke ʻano he mea hana kūikawā a maʻalahi hoʻi i ka kemika peptide, e hoʻoikaika ana i nā mea noiʻi e ʻimi a hoʻololi i ka hana guanidine no nā ʻano noiʻi ʻepekema a me nā therapeutic.