Fmoc-Cys(Akā)-OH CAS:67436-13-9

Hana ʻo Fmoc-Cys(Akā)-OH ma ke ʻano he mea hana kumu i ka peptide synthesis, ʻoi aku hoʻi i ka hana ʻana i nā peptides i loaʻa ka cysteine ​​me ka pololei. Pale ka hui pale Fmoc i ka hui amino, e hōʻoiaʻiʻo ana i nā hopena koho i ka wā o ka peptide coupling, ʻoiai ʻo ka hui butyl e hoʻohui i kahi papa pale hou i ka hui thiol. Hoʻohana nui nā kānaka noiʻi iā Fmoc-Cys(Akā)-OH i ka synthesizing peptides no nā noi like ʻole, me ka hoʻomohala ʻana i nā lāʻau lapaʻau peptide, bioconjugation, a me ka hoʻokumu ʻana i nā peptides me nā hiʻohiʻona kūkulu kikoʻī. ʻO kona kūlike me nā ʻano hana peptide synthesis maʻamau, ma nā hoʻolālā paʻa a me ka solution-phase, e hoʻonui i kona versatility i nā hana noiʻi like ʻole. ʻO ka wehe ʻana i nā hui pale i kāohi ʻia e ʻae i ka hoʻohui hoʻolālā o ka cysteine ​​​​i loko o nā moʻo peptide, e hoʻonui ana i ka laulā o nā peptides synthesizable. Eia kekahi, loaʻa iā Fmoc-Cys(Akā)-OH ka pono i ke aʻo ʻana i ka pelu ʻana o ka protein, ka hoʻokumu ʻana o ka disulfide bond, a me ka hoʻomohala ʻana i nā mea peptide. ʻO ka hoʻohana hoʻolālā o ka hui pale butyl e hiki ai i ka hoʻoponopono pololei ʻana i ka cysteine ​​reactivity, e hāʻawi ana i nā mea noiʻi i kahi mea hana waiwai no ka hoʻolālā ʻana i nā peptides me nā hoʻololi i hana ʻia. I ka hōʻuluʻulu manaʻo, kū ʻo Fmoc-Cys(But)-OH ma ke ʻano he mea hana maʻalahi a pono ʻole i ka kemika peptide, e hoʻoikaika ana i nā mea noiʻi e ʻimi a hoʻololi i ka reactivity cysteine ​​​​no kahi ākea o nā noi ʻepekema, e kālele ana i nā peptides e loaʻa ana kēia waikawa amino koʻikoʻi.