ʻO Fmoc-His(Fmoc)-OH CAS:98929-98-7

Hoʻohana nui ʻia ʻo Fmoc-His(Fmoc)-OH i ke kemika peptide, bioconjugation, a me ka noiʻi lāʻau lapaʻau no ka synthesis kūikawā o nā peptides waiwai histidine me nā waiwai a me nā hana kikoʻī. Ma ke ʻano he ʻāpana koʻikoʻi i ka synthesis peptide solid-phase, hiki iā ia ke hana i nā peptides no ke aʻo ʻana i ka hoʻopaʻa ʻana i ka metala, ka catalysis enzyme, a me nā pilina receptor-ligand. Hoʻohana nā kānaka noiʻi iā Fmoc-His(Fmoc)-OH e hoʻomohala i nā peptides no nā noi therapeutic, e like me ke kuhikuhi ʻana i nā kikowaena protein waiwai histidine i komo i nā ala maʻi a i ʻole he chelators no nā therapeutics i hoʻokumu ʻia i ka metala. ʻO ka maʻemaʻe kiʻekiʻe a me ka pale pālua o Fmoc-His(Fmoc)-OH e lilo ia i koho kūpono no ka hana ʻana i nā peptides me ka mana pololei ma luna o ke kūlana histidine a me ka reactivity. ʻO kona kūlike me nā ʻano hana peptide maʻamau a me nā protocols e hōʻoia i ka hoʻohui maʻalahi i nā kahe hana hoʻokolohua, e hoʻoikaika ana i nā ʻepekema e hana ʻenekinia i nā peptides waiwai histidine i hoʻopilikino ʻia i kā lākou mau pono hoʻokolohua. Inā hoʻohana ʻia ma ke kula nui a i ʻole ka ʻoihana, hāʻawi ʻo Fmoc-His(Fmoc)-OH i ka hoʻolaha ʻana i ka noiʻi peptide-based, ka hoʻomohala ʻana i nā lāʻau lapaʻau, a me ka ʻimi ʻana i nā kuleana like ʻole o ka histidine i nā ʻōnaehana olaola a me nā hana therapeutic.