Forskolin CAS:66575-29-9 Mea Hana Mea Hoʻolako

ʻO Forskolin kahi diterpene i hoʻokaʻawale ʻia mai Coleus forskohlii, nona nā waiwai vasodilating a me cardiostimulatory. Hoʻihoʻi hou ʻo Forskolin i nā mea loaʻa o ke kelepona ma ka hoʻoulu ʻana i ka enzyme adenylyl cyclase a me ka hoʻonui ʻana i nā pae intracellular o cAMP. ʻO Cyclic AMP (cAMP) kahi mea lawe hōʻailona koʻikoʻi e pono ai no ka pane olaola kūpono o nā kelepona i nā hormones, neurotransmitters, a me nā hōʻailona extracellular ʻē aʻe. ʻO Forskolin kahi diterpene kūlohelohe i hana ʻia e ka mea kanu Indian Coleus (C. forskohlii). Hoʻoulu pololei ia i ka adenylyl cyclase ma o kāna subunit catalytic a hoʻohana pinepine ʻia e hoʻokiʻekiʻe i nā pae o cAMP i nā ʻano like ʻole o nā kelepona paʻa a me nā hoʻomākaukau ʻiʻo.