Gabapentin CAS:60142-96-3 Mea Hana Mea Hoʻolako

ʻO Gabapentin kahi waikawa Amino e pili ana i ke ʻano me ka γ-Aminobutyric Acid (GABA), i hoʻolālā ʻia e hele i ka pale koko-lolo. Hoʻohana ʻia ma ke ʻano he anticonvulsant. Ua kuhikuhi ʻia hoʻi i nā maʻi sclerosis lehulehu e kāohi i ka dysesthesias a he mea pono paha i ka hōʻemi ʻana i ka ʻeha neuropathic i hoʻokumu ʻia e ka maʻi kanesa a me ka maʻi HIV. ʻAʻole ia e hoʻopaʻa i nā mea loaʻa GABA, ʻaʻole ia e hoʻohuli i ka neural uptake o GABA, a ʻaʻole hoʻi e kāohi i ka enzyme GABA-metabolizing, GABA transaminase. ʻAʻole like me GABA, ka mea ʻaʻole e hele ma waena o ka pale koko-lolo, komo ka gabapentin i loko o ka ʻōnaehana nerve waena a hoʻopaʻa i nā kahawai calcium voltage-gated α2δ-type. ʻAʻole ʻike ʻia ke ʻano no nā hopena analgesic a me anticonvulsant o gabapentin.