Hygromycin B CAS:31282-04-9 Kumukūʻai Mea Hana

He lāʻau antibiotic ʻo Hygromycin B i loaʻa mai ka bacteria Streptomyces hygroscopicus. Hoʻopuka ia i kona hopena ma ke kāohi ʻana i ka hana protein i loko o nā cell ma ke keakea ʻana i ka hana peptidyl transferase o ka ribosome. He kūpono ʻo Hygromycin B e kūʻē i kahi ākea o nā bacteria, fungi, a me nā cell eukaryotic kiʻekiʻe.

ʻO kahi hoʻohana nui o Hygromycin B ma ke ʻano he mea koho i ka biology molekala a me nā hoʻokolohua ʻenekinia genetic. Hoʻohana pinepine ʻia ia ma ke ʻano he māka hiki ke koho ʻia i ka hana ʻana o nā meaola transgenic, e like me nā mea kanu, nā holoholona, ​​​​a me nā bacteria. Ma ka hoʻolauna ʻana i kahi gene encoding resistance i ka Hygromycin B, hiki i nā mea noiʻi ke ʻike maʻalahi a koho i nā cell a i ʻole nā ​​​​ola i hoʻokomo pono i ka hoʻololi genetic i makemake ʻia.

No ka hoʻohana ʻana i ka Hygromycin B no ke koho ʻana, mālama pinepine ʻia nā pūnaewele a i ʻole nā ​​meaola me ka antibiotic. ʻO nā pūnaewele wale nō i hoʻohui pono i ka gene kū'ē e hiki ke ola a hoʻomau i ka ulu ʻana, ʻoiai e make ana nā pūnaewele i hoʻololi ʻole ʻia. ʻAe kēia i nā mea noiʻi e hoʻokaʻawale a hoʻolaha i nā pūnaewele i hoʻololi ʻia i ka genetics no ka nānā hou aku a i ʻole ka hoʻohana ʻana.

Ma waho aʻe o kona hoʻohana ʻana i ka ʻenekinia genetic, hoʻohana ʻia ʻo Hygromycin B ma ke ʻano he mea antibacterial a me antifungal i nā wahi noiʻi like ʻole. Hoʻohana ʻia ia i nā ʻōnaehana moʻomeheu cell e pale aku i ka haumia e nā bacteria, fungi, a me nā microorganism ʻē aʻe e hoʻopilikia paha i ka ulu ʻana a me ke aʻo ʻana o nā cell.