Linagliptin CAS:668270-12-0 Mea Hoʻolako Mea Hana

ʻO Linagliptin (TrajentaR, TradjentaTM, TrazentaTM, TrayentaTM) he waha, koho nui loa ia o ka dipeptidyl peptidase-4 a ʻo ia ka mea mua o kāna papa e hoʻopau nui ʻia ma ke ala nonrenal.Hōʻike ʻia ʻo Linagliptin no ka hoʻohana ʻana i kēlā me kēia lā no ka mālama ʻana i nā pākeke me ka maʻi diabetes type 2. Hana ʻo Linagliptin i ka hoʻohaʻahaʻa ʻana i ke kiʻekiʻe o ka glucose koko ma ke kāohi ʻana i ka enzyme DPP-4, a laila e pale ai i ka hōʻino ʻana o nā hormones incretin (glucagon-like peptide-1 [GLP] -1] a me ka glucose-dependent insulinotropic peptide) a me ka hoʻemi ʻana i nā huakaʻi glucose postprandial.