Linagliptin CAS:668270-12-0 Mea Hana Mea Hoʻolako

ʻO Linagliptin (TrajentaR, TradjentaTM, TrazentaTM, TrayentaTM) he mea hoʻopaʻa waha, koho nui o ka dipeptidyl peptidase-4 a ʻo ia ka mea mua o kona papa e hoʻopau nui ʻia ma o ke ala nonrenal. Hōʻike ʻia ʻo Linagliptin no ka hoʻohana ʻana i hoʻokahi manawa i ka lā no ka mālama ʻana i nā pākeke me ka maʻi diabetes mellitus type 2. Hana ʻo Linagliptin i ka hoʻohaʻahaʻa ʻana i nā pae glucose koko ma ka pale ʻana i ka enzyme DPP-4, no laila e pale ana i ka hōʻino ʻana o nā hormones incretin (glucagon-like peptide-1 [GLP-1] a me ka glucose-dependent insulinotropic peptide) a me ka hoʻēmi ʻana i nā excursions glucose postprandial.