ʻO Mecillinam CAS:32887-01-7

Hoʻohana pinepine ʻia ʻo Mecillinam i ka hana lapaʻau no ka mālama ʻana i nā maʻi ʻaʻai urinary maʻalahi (UTI) i hoʻokumu ʻia e nā bacteria Gram-negative susceptible, ʻoiai ʻo Escherichia coli. ʻO kona ʻano hana haiki e ʻae ai i ka lāʻau lapaʻau i kuhikuhi ʻia e kūʻē i nā uropathogens maʻamau me ka hoʻēmi ʻana i ka hoʻopilikia ʻana i ka flora maʻamau. Makemake pinepine ʻia ʻo Mecillinam no nā UTI ma muli o kona pono, ka palekana, a me ka hiki ke hoʻoulu i ke kūʻē. Ma waho aʻe o nā UTI, hoʻohana ʻia ʻo mecillinam no ka hoʻokele ʻana i nā maʻi kūloko ʻē aʻe, e like me ka prostatitis a me nā maʻi ʻaʻai hanu haʻahaʻa, kahi e pili ai nā bacteria Gram-negative susceptible. ʻO kāna hana koho e kūʻē i ka Enterobacteriaceae e lilo ia i koho waiwai nui i ka mālama ʻana i kēia mau maʻi kikoʻī me ka pale ʻana i ka hoʻohana ʻana i ka antibiotic ākea ākea. ʻO ka hoʻohui waha o Mecillinam a me nā waiwai pharmacokinetic maikaʻi e maʻalahi ai no ka mālama ʻana i nā maʻi maʻalahi a me ke kaulike, e ʻae ana i nā mea maʻi e hoʻopau pono i kā lākou papa hana. ʻO kona pono i hoʻokumu maikaʻi ʻia i ka hoʻopaʻa ʻana i nā pathogens Gram-negative e hōʻike ana i kona koʻikoʻi i ka hoʻokele ʻana i nā maʻi bacteria kūloko. Eia kekahi, hoʻohana ʻia ka mecillinam i kekahi mau ʻano hana prophylactic e pale aku i nā UTI hou a i ʻole he prophylaxis perioperative i nā kaʻina hana ʻoki kahi e hoʻoweliweli ai ka bacteria Gram-negative i ka maʻi. ʻO kona hiki ke hoʻokō i nā kiʻekiʻe kiʻekiʻe i loko o nā ʻiʻo urinary a hakakā pono i nā uropathogens e lilo ia i mea prophylactic waiwai nui i nā kūlana lapaʻau kikoʻī. Ma keʻano holoʻokoʻa, lawelawe ʻo mecillinam ma ke ʻano he koho antibiotic waiwai nui i ka mālama ʻana i nā maʻi kūloko i hoʻokumu ʻia e nā bacteria Gram-negative susceptible, e hāʻawi ana i nā kauka i kahi ala therapeutic i kuhikuhi ʻia a maikaʻi me ka haʻahaʻa o ka pilikia o ka ulu ʻana o ke kūʻē. ʻO kona niche ma ke ʻano he mea hana spectrum haiki e lilo ia i mea hana koʻikoʻi i nā hana mālama antimicrobial, e paipai ana i ka hoʻohana antibiotic kūpono a me ka hoʻēmi ʻana i ka puka ʻana mai o nā meaola multidrug-resistant.