methyl 4-oxo-3,4-dihydroquinazoline-7-carboxylate CAS:313535-84-1

He kuleana koʻikoʻi ko Methyl 4-oxo-3,4-dihydroquinazoline-7-carboxylate i ka synthesis o nā lāʻau lapaʻau, e lawelawe ana ma ke ʻano he mea nui no ka laulā o nā hui bioactive. ʻO kona scaffold quinazoline kahi motif structural maʻamau i loaʻa i nā lāʻau lapaʻau he nui, me nā mea anticancer, antihistamines, a me nā kinase inhibitors. Ma ka hoʻohana ʻana i ka versatility o kēia hui, hiki i nā chemists ke komo i kahi plethora o nā ala synthetic e hana i nā moho lāʻau lapaʻau hou me nā pono therapeutic hiki. Eia kekahi, ʻo kona hoʻokomo ʻana i loko o nā hana ʻike lāʻau lapaʻau e hiki ai ke hoʻololi i ka ʻōnaehana quinazoline e hana i nā derivatives me nā waiwai pharmacological i hoʻomaikaʻi ʻia, e like me ka potency i hoʻomaikaʻi ʻia a me ke koho ʻana. Eia kekahi, hoʻohana ʻia kēia hui i ka noiʻi kula a me nā hoʻonohonoho ʻoihana e ʻimi i nā mea kemika hou me nā ʻano pharmacological hoʻohiki. ʻO ka hilinaʻi a me ke kūlike o ka methyl 4-oxo-3,4-dihydroquinazoline-7-carboxylate e lilo ia i mea hana pono ʻole i ka ʻoihana lāʻau lapaʻau, e hoʻomaʻamaʻa ana i ka synthesis pono o nā molekala paʻakikī me ka hōʻoia ʻana i nā hopena hiki ke hana hou ʻia. Ma ke ʻano he ʻāpana kumu i ka kemika lāʻau lapaʻau, hiki iā ia ke hoʻoikaika i nā kānaka ʻepekema e hoʻonui i ka wahi kemika o nā moho lāʻau lapaʻau kūpono a hoʻolaha i ka hoʻomohala ʻana o nā ʻano lapaʻau hou no nā ʻano maʻi like ʻole.