ʻO ka Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate CAS:328086-60-8

Hoʻohana ʻia ʻo Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate ma ke ʻano he kikowaena koʻikoʻi no ka synthesis o nā peptide derivatives a me nā hui lāʻau lapaʻau. Hāʻawi kāna mau hui hana kikoʻī a me ka stereochemistry i ke komo koʻikoʻi i nā peptides paʻakikī a me nā peptidomimetics me ka bioactivity hiki a me nā waiwai like me ka lāʻau. Hoʻohana nā kānaka noiʻi i kona mau hiʻohiʻona hoʻonohonoho e hoʻolauna i nā koena amino acid a me nā moieties heterocyclic i loko o nā moʻo peptide, e hoʻololi ana i kā lākou pilina olaola a me ka kikoʻī o ka pahuhopu. Loaʻa i ka hui nā noi i loko o ka kemika peptide, kahi e lawelawe ai ma ke ʻano he poloka hale no ka synthesis peptide, ka hui peptide solid-phase, a me ka hoʻolālā lāʻau peptide. Hiki i ka Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate ke kūkulu ʻana i nā hale waihona puke peptide, nā peptide mimetics, a me nā therapeutics e pili ana i ka peptide e kuhikuhi ana i nā ala olaola like ʻole a me nā pahuhopu molekala. ʻO kāna kuleana i ka hoʻololi ʻana a me ka hoʻonui ʻana i ka peptide e kōkua i ka hoʻomohala ʻana i nā moho lāʻau lapaʻau hou, nā diagnostics, a me nā mea hana biochemical. I loko o ka ʻoihana lāʻau lapaʻau, hoʻohana ʻia ʻo Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate i ka synthesis o nā lāʻau peptidic, nā peptide conjugates, a me nā prodrugs e pili ana i ka peptide. ʻO kona komo ʻana i ka noiʻi peptide a me ka ʻike ʻana i nā lāʻau lapaʻau e hiki ai ke ʻimi i nā hōʻailona peptide-mediated, nā pilina receptor, a me nā hana therapeutic ma nā wahi e like me ka oncology, immunology, a me ka neurology. Ma ka hoʻokomo ʻana i kēia hui i loko o nā ʻano peptide, hiki i nā kānaka ʻepekema ke hoʻonui i nā waiwai pharmacokinetic, ke kūpaʻa olaola, a me ka pili pono o nā lāʻau lapaʻau e pili ana i ka peptide, e hoʻonui ana i ka laulā o nā peptide therapeutics a me nā lāʻau lapaʻau pilikino.