N-methyl-2,2,2-trifluoroacetamide CAS:815-06-5

ʻIke ʻia ʻo N-Methyl-2,2,2-trifluoroacetamide (NMTFA) e kona ʻano molekala, nona kahi hui trifluoromethyl (-CF3) i hoʻopili ʻia i kahi iwi kuamoʻo acetamide (-CONHCH3). Hāʻawi kēia ʻano i ke kūpaʻa koʻikoʻi a me ka reactivity iā NMTFA, e kūpono ai no nā ʻano noi kemika like ʻole. Loaʻa pinepine ʻo NMTFA ma ke ʻano he paʻa crystalline me kahi kiko heheʻe o kahi o 62 ° C a hōʻike i ka solubility maikaʻi i nā solvents organik polar e like me ka acetone a me ka ethanol. ʻO kona kūpaʻa ma lalo o nā kūlana like ʻole e ʻae ai i kona hoʻohana pono ʻana i nā noiʻi hale hana a me nā kaʻina hana ʻoihana. Hoʻohana Organic Synthesis: Hana ʻo NMTFA ma ke ʻano he waena koʻikoʻi i ka synthesis organik, ʻoi aku hoʻi i ka hoʻokomo ʻana o nā hui trifluoromethyl i loko o nā mole organik. He mea nui kēia hiki no ka hoʻomohala ʻana i nā lāʻau lapaʻau, nā agrochemicals, a me nā kemika kūikawā me ka hana olaola i hoʻonui ʻia a me ke kūpaʻa kemika. Kemika lāʻau lapaʻau: I nā noi lāʻau lapaʻau, hoʻohana ʻia ʻo NMTFA ma ke ʻano he precursor i ka synthesis o nā mea hana lāʻau lapaʻau ikaika (APIs) ma muli o kona hiki ke hāʻawi i nā waiwai pharmacological i makemake ʻia. He kuleana koʻikoʻi kona i ke kemika lāʻau lapaʻau ma o ka hiki ʻana ke hoʻololi i nā molekala lāʻau lapaʻau e hoʻonui i ka pono a hōʻemi i ka hiki ke hoʻololi i ka metabolic. Nā Kemika Kūikawā: Loaʻa ka noi o NMTFA i ka hana ʻana o nā kemika kūikawā e like me nā surfactants, plasticizers, a me nā mea waena paʻakikī i hoʻohana ʻia i ka synthesis o nā agrochemicals a me nā kemika maikaʻi. ʻO kona versatility i nā hoʻololi kemika e lilo ia i mea waiwai i nā formulations kahi e pono ai ka mana pololei ma luna o ka hoʻonohonoho molekala a me ka hana. Hoʻohui ʻia ka Synthesis N-Methyl-2,2,2-trifluoroacetamide ma o ka hopena o ka trifluoroacetic acid me ka methylamine. Pili kēia kaʻina hana i ka condensation o ka trifluoroacetic acid me ka methylamine ma lalo o nā kūlana i kāohi ʻia e hana iā NMTFA. Hoʻomau pinepine ka hopena i ke alo o kahi catalyst kūpono e hoʻomaʻamaʻa i ka hoʻokumu ʻana o ka pilina amide. Hoʻohana ʻia nā ʻano hoʻomaʻemaʻe e like me ka recrystallization a i ʻole chromatography e loaʻa ai ka NMTFA i ka maʻemaʻe kiʻekiʻe i kūpono no nā noi ʻoihana. ʻO ke ala synthesis pololei a me ka loaʻa ʻana o nā mea maka e hāʻawi i kona kumukūʻai kūpono a me ka hoʻohana ākea ʻana i ka noiʻi kula a me nā kaʻina hana ʻoihana. I ka hōʻuluʻulu manaʻo, he hui like ʻole ʻo N-methyl-2,2,2-trifluoroacetamide me nā noi koʻikoʻi i ka synthesis organik, kemika lāʻau lapaʻau, a me ka hana ʻana i nā kemika kūikawā. ʻO kona mau waiwai kemika kū hoʻokahi, me ke kūpaʻa, ka reactivity, a me ka maʻalahi o ka synthesis, e hāʻawi i kona koʻikoʻi i ka hoʻolaha ʻana i nā ʻenehana ma nā ʻāpana ʻoihana like ʻole a me nā aʻo ʻepekema.