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N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium paʻakai CAS:66992-27-6
ʻO N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium paʻakai, ʻike ʻia hoʻi ʻo HEPES sodium paʻakai, he mea hoʻohui kemika i hoʻohana mau ʻia ma ke ʻano he mea hoʻopaʻa pH i loko o nā laboratories biological a me kemika.Kōkua ia i ka mālama ʻana i kahi pae pH paʻa, e kūpono ia no nā noi e like me ka moʻomeheu cell, ka enzyme assays, protein study, electrophoresis, a me nā ʻano hana lāʻau.ʻO ka paʻakai sodium HEPES e hōʻoia i nā kūlana kūpono no nā kaʻina hana olaola a hoʻonui i ka pololei a me ka hilinaʻi o nā hopena hoʻokolohua.
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2′-(4-METHYLUMBELLIFERYL)-ALPHA-DN-ACETYLNEURAMINIC ACID SODIUM SALT CAS:76204-02-9
2'-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid sodium paʻakai he mea hoʻohui kemika i hoʻohana mau ʻia i nā hoʻokolohua diagnostic a me nā noiʻi.ʻO ia ka mea i hoʻopaʻa inoa ʻia o ka sialic acid, kahi ʻano mole mole kalapona i loaʻa ma ka ʻili o nā cell.
Hoʻohana ʻia kēia pūhui ma ke ʻano he substrate no nā enzymes i kapa ʻia ʻo neuraminidases, e hana ana e hoʻoneʻe i nā koena waikawa sialic mai nā glycoproteins a me glycolipids.Ke hana kēia mau enzymes i ka paʻakai sodium 2′-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid, hoʻokuʻu ia i kahi huahana fluorescent i kapa ʻia ʻo 4-methylumbelliferone.
Hiki ke ana a helu ʻia ka fluorescence i hana ʻia e ka pūhui, e hāʻawi ana i ka ʻike e pili ana i ka hana o nā enzymes neuraminidase.He mea maikaʻi loa kēia i ke aʻo ʻana i nā maʻi like ʻole a me nā kūlana e pili ana me ka aberrant sialic acid metabolism.
Hoʻohana ʻia ka pūhui no nā kumu diagnostic, e like me ka ʻike ʻana i nā maʻi viral e pili ana i ka hana neuraminidase.I loko o kēia mau ho'āʻo, hoʻohana ʻia ka pūhui e ʻike i ka hiki ʻana o nā maʻi viral kikoʻī a i ʻole ka loiloi i ka pono o nā neuraminidase inhibitors i nā lāʻau antiviral.
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TAPSO CAS:68399-81-5 Kumukūʻai Mea Hana
ʻO TAPSO (3-[N-tris(hydroxymethyl)methyl]amino]-2-hydroxypropanesulfonic acid) he zwitterionic buffer i hoʻohana mau ʻia i ka noiʻi olaola a me ka biochemical.He mea hoʻopololei maikaʻi me kahi pKa kokoke i ka pH physiological, kūpono ia no ka mālama ʻana i kahi pH paʻa i nā hoʻokolohua biological.Hoʻohana pinepine ʻia ʻo TAPSO i ka hoʻomaʻemaʻe ʻana i ka protein, nā hoʻokolohua enzyme, ka moʻomeheu cell, a me nā noi electrophoresis.ʻO kona hoʻoheheʻe wai kiʻekiʻe a me ka hoʻohaʻahaʻa haʻahaʻa i nā kaʻina hana biological e lilo ia i mea koho kaulana i ke kaiāulu ʻepekema.Ua ʻike ʻia ʻo TAPSO no kona hopena liʻiliʻi i ka hana enzyme a hoʻohana pinepine ʻia ma ke ʻano he mea ʻokoʻa i nā mea hoʻolale ʻē aʻe e like me Tris a i ʻole phosphate buffers.
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N-Acetyl-L-cysteine CAS:616-91-1
ʻO ka N-Acetyl-L-cysteine (NAC) kahi ʻano hoʻololi o ka cysteine amino acid.Hāʻawi ia i kahi kumu o ka cysteine a hiki ke hoʻololi koke ʻia i ka tripeptide glutathione, kahi antioxidant ikaika i ke kino.ʻIke ʻia ʻo NAC no kāna mau antioxidant a me nā waiwai mucolytic, e hoʻohana pono ai i nā noi olakino.
Ma ke ʻano he antioxidant, kōkua ʻo NAC i ka pale ʻana i nā cell mai ka pōʻino i hoʻoiho ʻia e nā radical manuahi, nā ʻano oxygen reactive, a me nā toxins.Kākoʻo ia i ka glutathione synthesis, kahi mea koʻikoʻi i nā kaʻina detoxification o ke kino a me ka mālama ʻana i kahi ʻōnaehana olakino olakino.
Ua aʻo ʻia ʻo NAC no kāna mau pono kūpono i ke olakino hanu, ʻoi aku hoʻi no nā poʻe me nā kūlana e like me ka bronchitis maʻi, COPD, a me ka cystic fibrosis.Hoʻohana mau ʻia ʻo ia ma ke ʻano he expectorant e kōkua i ka hoʻokaʻawale ʻana a me ka hoʻokaʻawale ʻana i ka ʻōpala, e maʻalahi ai ka hoʻomaʻemaʻe ʻana i nā alaloa.
Eia kekahi, ua hōʻike ʻo NAC i ka ʻōlelo hoʻohiki i ke kākoʻo ʻana i ke olakino o ke ake ma ke kōkua ʻana i ka wehe ʻana i nā mea ʻona, e like me ka acetaminophen, kahi mea hoʻomaha ʻeha maʻamau.Loaʻa paha nā hopena pale i ka pōʻino o ka ate ma muli o ka inu ʻona.
Ma kahi o kāna mau antioxidant a me nā mea kākoʻo hanu, ua ʻimi ʻia ʻo NAC no kāna mau pono kūpono i ke olakino noʻonoʻo.Ke hōʻike nei kekahi mau noiʻi he hopena maikaʻi paha ia i nā maʻi ʻino, e like me ke kaumaha a me ka obsessive-compulsive disorder (OCD).
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PIPES CAS:5625-37-6 Kumukūʻai Mea Hana
ʻO PIPES (piperazine-1,4-bisethanesulfonic acid) he zwitterionic buffering pūhui i hoʻohana mau ʻia i ka noiʻi olaola a me ka biochemical.He paʻa pH maikaʻi ia me ka mana kiʻekiʻe no ka mālama ʻana i nā kūlana pH kūpaʻa i ka pae pH o 6.1 a 7.5.He liʻiliʻi ka hoʻopilikia ʻana o PIPES me nā biomolecules a kūpono ia no ka hoʻāʻo ʻana i ka wela.Hoʻohana pinepine ʻia i nā ʻenehana electrophoresis gel a me ka hoʻokumu ʻana i ka lāʻau lapaʻau ma ke ʻano he stabilizing agent.Ma ke ʻano holoʻokoʻa, ʻo PIPES kahi hui maʻalahi a hoʻohana nui ʻia i nā ʻano hoʻokolohua like ʻole.
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2′,6′-DiMethylcarbonylphenyl-10-sulfopropylacridiniuM-9-carboxylate 4′-NHS Ester CAS:194357-64-7
ʻO 2′,6′-DiMethylcarbonylphenyl-10-sulfopropylacridinium-9-carboxylate 4′-NHS ester he mea hoʻohui kemika me kahi ʻano molekala paʻakikī.Loaʻa iā ia kahi hui sulfopropylacridinium a me kahi hui hana carboxylate ester.ʻO ka loaʻa ʻana o ka ester moiety e hōʻike ana he reactive a hiki ke hoʻohana ʻia ma ke ʻano he mea hōʻailona a hoʻololi paha no nā biomolecules.
Hōʻike ka pūʻulu sulfopropylacridinium o ka pūhui he mea hiki ke hoʻohana ʻia i nā hoʻokolohua fluorescence-based assays, kahi hiki ke hoʻohana ʻia ma ke ʻano he ʻimi fluorescent a i ʻole ka wai no ka ʻike ʻana a me ka nānā ʻana i nā biomolecules.He mea pili paha ia i ka noiʻi ʻana i nā kaʻina kelepona, e like me ka hōʻailona calcium intracellular.
ʻO ka hoʻokomo ʻana o ka pūʻulu ester NHS e hōʻike ana hiki iā ia ke hana me nā amine mua, e like me nā mea i loaʻa i loko o nā protein a i ʻole nā peptides, e hana i nā paʻa amide paʻa.Hoʻohana ʻia kēia reactivity no nā noi bioconjugation, kahi hiki ke hoʻohana ʻia e lepili a hoʻololi i nā biomolecules me nā molekole hana ʻē aʻe, e like me nā fluorophores a i ʻole nā hōʻailona.
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5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide CAS:4264-82-8
ʻO 5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide he mea hoʻohui i hoʻohana ʻia i loko o nā haʻawina biochemical like ʻole, ʻoi loa no ka ʻike a me ka ʻike ʻana i ka hana enzyme.He substrate ia e hiki ke hoʻoheheʻe ʻia e nā enzyme kikoʻī, ka hopena i ka hoʻokuʻu ʻana i kahi huahana kala a fluorescent paha.
Hoʻohana mau ʻia kēia pūhui i nā hoʻāʻo e ʻike i ke alo a me ka hana o nā enzymes e like me beta-galactosidase a me beta-glucuronidase.Hoʻokaʻawale kēia mau enzymes i nā hui acetyl a me glucosaminide mai ka substrate, e alakaʻi ana i ke kūkulu ʻana i kahi chromophore uliuli a ʻōmaʻomaʻo paha.
ʻO ka hana kūikawā o 5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide e hiki ai ke ʻike maʻalahi a me ka helu ʻana o ka hana enzyme.ʻO kona hoʻohana ʻana i nā ʻano hana hoʻokolohua like ʻole, me ka histochemistry, immunohistochemistry, a me nā hoʻāʻo ʻana i ke kelepona, ua kōkua i ka ʻike maikaʻi ʻana i nā hana enzyme.
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Paʻakai Sodium CAS:139-41-3 Kumukūʻai Mea Hana
N,N-Bis(2-hydroxyethyl)glycine sodium paʻakai he mea hoʻohui kemika i hoʻohana ʻia ma ke ʻano he mea hoʻopaʻa i nā noi biochemical a me biophysical like ʻole.Kōkua ia i ka mālama ʻana i ka pae pH paʻa i nā kūlana hoʻokolohua, e hoʻohana pono ai i nā haʻawina enzyme, ka noiʻi protein, ka moʻomeheu cell, a me nā ʻenehana blotting Western.
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Spinosad CAS:131929-60-7 Mea Hoʻolako Mea Hana
ʻO Spinosad kahi hui 5 nicotinic acetylcholine receptor agonist, ka mea e hoʻoulu ai i nā ʻiʻo a me nā haʻalulu lua i ka hoʻoulu ʻana o ka neuron motor.ʻO ka loaʻa ʻana o ka ʻike lōʻihi ke kumu o ka lolo a me ka make ʻana o ka peʻa.Hoʻomaka ka make ʻana o ka peʻa i loko o 30 mau minuke o ka hoʻopaʻa ʻana a ma 4 mau hola e pau ai.ʻAʻole pili ʻo Spinosad me nā wahi hoʻopaʻa ʻana o nā mea hana insecticidal ʻē aʻe (GABA-ergic a i ʻole nicotinic).
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Rotenone CAS:83-79-4 Mea Hoʻolako Mea Hana
ʻO Rotenone ka ʻōpū a me ka lāʻau ʻawaʻawa no nā arthropods.ʻO kāna hana kīkī wikiwiki e hoʻemi ʻia i ka loaʻa ʻana o ka nicotinamide adenine dinucleotide e lawelawe ma ke ʻano he cofactor i nā ala biochemical like ʻole me ka pōʻai Krebs, no laila ke kāohi nei i nā enzymes respiratory mitochondrial.
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Diazinon CAS:333-41-5 Mea Hoʻolako Mea Hana
Loaʻa ka Diazinon ma ke ʻano o ka wai kala ʻole a ʻeleʻele paha.Hiki ke hoʻoheheʻe ʻia i ka wai akā hiki ke hoʻoheheʻe ʻia i ka petroleum ether, ka waiʻona, a me ka benzene.Hoʻohana ʻia ʻo Diazinon no ka mālama ʻana i nā ʻano ʻano mahiʻai a me nā pest home.Hoʻopili kēia i nā pests ma ka lepo, ma luna o nā mea kanu nani, nā huaʻai, nā mea kanu, a me nā mea kanu a me nā pest home e like me nā nalo, nā ʻauʻau, a me nā moa.
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Avermectin CAS:71751-41-2 Mea Hoʻolako Mea Hana
ʻO Abamectin (Avermectin) kahi mea ʻawaʻawa aʻalolo.ʻO kāna hana ke kuhikuhi nei i ka GABAA receptor o ka insect neuron synapse a i ʻole neuromuscular synapse, ke keʻakeʻa nei i ka hoʻololi ʻana o ka ʻike o nā hopena nerve, ʻo ia hoʻi ka hoʻoulu ʻana i nā aʻalolo e hoʻokuʻu i ka neurotransmitter inhibitor γ-aminobutyric acid (GA-BA), e koi ana i ka wehe ākea o ka. ʻO ke kahawai chloride-gated GABA me ka hopena hoʻonāwaliwali.
