2′-(4-METHYLUMBELLIFERYL)-ALPHA-DN-ACETYLNEURAMINIC ACID SODIUM SALT CAS:76204-02-9

ʻO ka paʻakai sodium 2′-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid kahi hui kemika i hoʻohana pinepine ʻia i nā hoʻāʻo diagnostic a me nā noiʻi. He huaʻōlelo fluorescent ia o ka waikawa sialic, kahi ʻano molekala carbohydrate i loaʻa ma ka ʻili o nā cell.

Hoʻohana ʻia kēia hui ma ke ʻano he substrate no nā enzymes i kapa ʻia ʻo neuraminidases, kahi e hana ai e wehe i nā koena waikawa sialic mai nā glycoproteins a me nā glycolipids. Ke hana kēia mau enzymes ma ka paʻakai sodium 2′-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid, hoʻokuʻu ia i kahi huahana fluorescent i ʻike ʻia ʻo 4-methylumbelliferone.

Hiki ke ana ʻia a helu ʻia ka fluorescence i hana ʻia e ka hui, e hāʻawi ana i ka ʻike e pili ana i ka hana o nā enzymes neuraminidase. He mea pono loa kēia i ke aʻo ʻana i nā maʻi like ʻole a me nā kūlana e pili ana me ka metabolism waikawa sialic aberrant.

Hoʻohana ʻia ka hui no nā kumu diagnostics, e like me ka ʻike ʻana i nā maʻi viral e pili ana i ka hana neuraminidase. Ma kēia mau assays, hoʻohana ʻia ka hui e ʻike i ke alo o nā ʻano viral kikoʻī a i ʻole e loiloi i ka pono o nā mea hoʻopaʻa neuraminidase i nā lāʻau antiviral.

Kauoha a Noi paha i ka ʻŌlelo Kūʻai

Nā kikoʻī huahana

Nā Lepili Huahana

Hoʻohana a me ka hopena

Ka Hoʻāʻo Hana Neuraminidase: Hoʻohana pinepine ʻia kēia hui e ana i ka hana o nā enzyme neuraminidase i loko o nā laʻana olaola. Ma ka nānā ʻana i ka fluorescence i hana ʻia, hiki i nā mea noiʻi ke hoʻoholo i ka pae o ka hana neuraminidase, hiki ke kōkua i ke aʻo ʻana i nā maʻi a me nā kūlana like ʻole.

Ka ʻIke ʻana i ka Maʻi Viral: Nui nā maʻi viral, me ka maʻi influenza, e pili ana i ka hana neuraminidase. Hiki ke hoʻohana ʻia kēia hui e ʻike a helu i ke alo o nā ʻano viral kikoʻī ma ke ana ʻana i ka hana fluorescent. He mea pono loa ia i ka loiloi ʻana i ka pono o nā mea hoʻopaʻa neuraminidase i nā lāʻau antiviral.

Ka Nānā ʻana i ka Glycosylation: He ʻāpana koʻikoʻi ka waikawa sialic o nā glycoproteins a me nā glycolipids. Ma ka hoʻohui ʻana i ka paʻakai sodium 2'-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid i nā hoʻokolohua, hiki i nā mea noiʻi ke loaʻa ka ʻike i ka metabolism waikawa sialic, nā ʻano glycosylation, a me nā kaʻina hana physiological e pili ana.

Ka ʻIke ʻana i nā Lāʻau Lapaʻau: ʻO nā mea hoʻopaʻa Neuraminidase kahi papa o nā lāʻau i hoʻohana ʻia i ka mālama ʻana i nā maʻi viral. Hiki ke hoʻohana ʻia kēia hui i nā haʻawina ʻike lāʻau lapaʻau, e kōkua ana i nā mea noiʻi e ʻike a loiloi i nā mea hoʻopaʻa hiki i ka hana neuraminidase.

Hoʻopili Huahana:

ʻIke Hou Aʻe:

Hoʻonohonoho ʻana	C21H26NNaO11
Hoʻāʻo	99%
helehelena	Pauka keʻokeʻo
Helu CAS.	76204-02-9
Hoʻopili ʻana	Liʻiliʻi a nui
Ola Papa	2 mau makahiki
Ka Waihona	E mālama i kahi maloʻo a me kahi anuanu
Palapala hōʻoia	ISO.