ʻO Pyridoxal-5′-phosphate monohydrate CAS:41468-25-1

ʻO Pyridoxal-5′-phosphate monohydrate, i ʻike ʻia hoʻi ʻo PLP, ke ʻano hana o ka huaora B6. He coenzyme koʻikoʻi ia e pili ana i nā ʻano hana enzymatic like ʻole i loko o ke kino. He kuleana koʻikoʻi ko PLP i ka metabolism amino acid, ka synthesis neurotransmitter, a me ka synthesis o heme, kahi ʻāpana o ka hemoglobin.

Hana ʻo PLP ma ke ʻano he coenzyme ma o ka hoʻopaʻa ʻana i nā enzymes kikoʻī a me ke kōkua ʻana i nā hopena kemika. Hana ia ma ke ʻano he mea hoʻoulu, e kōkua ana i ka hoʻololi ʻana o nā mea like ʻole, e like me nā waikawa amino, i nā huahana like ʻole. He mea nui loa ka PLP i ka metabolism o nā waikawa amino, e like me ka hoʻololi ʻana o ka tryptophan i serotonin, a i ʻole ka haki ʻana o ka glycine i serine.

Ma waho aʻe o kāna kuleana i ka metabolism amino acid, pili pū ka PLP i ka synthesis o nā neurotransmitters e like me dopamine, norepinephrine, a me ka gamma-aminobutyric acid (GABA). He mea nui kēia mau neurotransmitters no ka hana kūpono o ka lolo a pili i ka hoʻoponopono ʻana i ke ʻano, ka ʻike, a me ka hoʻoili ʻana o nā hōʻailona ma waena o nā cell nerve.

Eia kekahi, pono ka PLP no ka hana ʻana o ka heme, kahi ʻāpana o ka hemoglobin i loaʻa i loko o nā hunaola koko ʻulaʻula. ʻO ka Hemoglobin ke kuleana no ka lawe ʻana i ka oxygen ma ke kino holoʻokoʻa, e hana ana i ka PLP he mea nui no ka mālama ʻana i nā pae oxygen maʻamau a me ka hōʻoia ʻana i ka hana pono o nā ʻano kino a me nā ʻiʻo like ʻole.

Ma muli o kona koʻikoʻi i nā kaʻina hana biochemical he nui, ua ʻōlelo ʻia ka hoʻopihapiha PLP i kekahi manawa no nā poʻe me kekahi mau kūlana olakino a i ʻole nā ​​​​hemahema e hoʻopilikia ai i ka metabolism vitamin B6. Loaʻa ia ma ke ʻano hoʻopihapiha a hiki ke kuhikuhi ʻia e nā mea lawelawe olakino no nā pono kikoʻī.