(R)-4,5,6,7-Tetrahydro-1H-indazol-5-aminehydrochloride CAS:1291790-29-8

ʻO (R)-4,5,6,7-tetrahydro-1H-indazol-5-amine hydrochloride e lawelawe ana ma ke ʻano he waena koʻikoʻi i ka synthesis o nā hui paʻakikī, bioactive me nā noi lāʻau lapaʻau hiki. ʻO kona ʻano chiral a me nā hiʻohiʻona hoʻonohonoho kū hoʻokahi e hoʻonoho iā ia ma ke ʻano he ʻāpana koʻikoʻi no ka hoʻokumu ʻana i nā hui enantiopure, he mea nui ia i ka hoʻomohala ʻana i ka lāʻau. Ma ka hoʻohui ʻana i kēia poloka hale i loko o nā ʻōnaehana molekala, hiki i nā mea noiʻi ke ʻimi i nā moho lāʻau hou e kuhikuhi ana i nā wahi therapeutic e like me nā maʻi ʻōnaehana nerve waena, ka hoʻokele ʻeha, a i ʻole nā ​​​​kūlana psychiatric. I loko o ke kemika lāʻau lapaʻau, hiki i kēia hui ke lawelawe ma ke ʻano he wahi hoʻomaka no ka hoʻolālā ʻana i nā moho lāʻau hiki, e hoʻohana ana i kāna stereochemistry e hoʻololi i ka hana olaola a me nā waiwai pharmacokinetic. Hoʻonui ke ʻano paʻakai hydrochloride i kona kūpaʻa a me ka solubility, e kūpono ai no nā kaʻina hana synthetic like ʻole a me nā hoʻāʻo olaola, e hoʻohui ana i kona pono i ka hoʻomohala ʻana i ka lāʻau. Eia kekahi, ma nā wahi hoʻonaʻauao a me nā ʻoihana, hiki i nā mea noiʻi ke hoʻohana i kēia poloka hale e hoʻomākaukau i nā hale waihona puke o nā derivatives like ʻole no nā haʻawina pilina hana-hana, e hoʻomaʻamaʻa ana i ka ʻike ʻana i nā hui alakaʻi me nā hopena olaola i makemake ʻia. ʻO kona kuleana i ka synthesis kemika e hoʻonui i ka hana ʻana o nā waena lāʻau lapaʻau a me ka hoʻomohala ʻana i nā ʻano hana synthetic hou, e hōʻike ana i kona pono ākea ma waena o nā aʻo ʻepekema. Ma keʻano holoʻokoʻa, he kuleana koʻikoʻi ko (R)-4,5,6,7-tetrahydro-1H-indazol-5-amine hydrochloride i ka ʻimi ʻana i ka ʻike lāʻau lapaʻau hou a me ka synthesis asymmetric, e hāʻawi ana i kahi kahua no ka hoʻomohala ʻana i nā molekala biologically active like ʻole a me nā mea lapaʻau waena.