ʻO Rapamycin mai Streptomyces hygroscopicus CAS: 53123-88-9

Nā hopena immunomodulatory: Kāohi ʻo Rapamycin i ka hoʻoulu ʻana a me ka hoʻonui ʻana o nā T-cell, he mea nui ia no nā pane pale. ʻO kēia hopena immunosuppressive e lilo ia i mea pono i ka hoʻoili ʻana o nā kino e pale aku i ka hōʻole ʻana.

Hana Kūʻē i ke Kanesa: Ua hōʻike ʻo Rapamycin i ka hiki ke lilo i mea kūʻē i ke kanesa. Hoʻopaʻa ia i ka protein mTOR, ka mea e pili ana i ka ulu ʻana a me ka mahele ʻana o nā cell. Ma ke kuhikuhi ʻana iā mTOR, kōkua ka rapamycin i ka kaohi ʻana i ka ulu nui ʻana o nā cell cancer. Ua aʻo ʻia no nā ʻano kanesa like ʻole, me ka umauma, ka prostate, ka māmā, a me ka renal cell carcinoma.

Ka Lapaʻau ʻana i nā Maʻi Kakaʻikahi: Ua ʻāpono ʻia ʻo Rapamycin no ka mālama ʻana i kekahi mau maʻi kakaʻikahi, e like me ka lymphangioleiomyomatosis (LAM) a me ka tuberous sclerosis complex (TSC). Pili kēia mau kūlana i ka ulu ʻana o nā cell ma nā ʻano kino like ʻole, a kōkua ka rapamycin i ka kaohi ʻana i nā hōʻailona a me ka holomua.

Nā hopena anti-inflammatory: Ua hōʻike ʻo Rapamycin i nā waiwai anti-inflammatory. Hiki iā ia ke kāohi i kekahi mau cell immune a me nā protein inflammatory, kahi mea pono paha i nā kūlana e pili ana i ka mumū mau, e like me nā maʻi autoimmune.

Nā Maʻi Neurological: Hōʻike ka noiʻi he hiki i ka rapamycin ke mālama i nā maʻi neurodegenerative e like me ka maʻi Alzheimer a me ka maʻi Parkinson. Ua hōʻike ia i nā hopena neuroprotective a me nā anti-aging i nā haʻawina preclinical, akā pono ka noiʻi hou aku.

Pale i ka ʻelemakule a me ke ola lōʻihi: Ua loaʻa i ka Rapamycin ka nānā ʻia no kona hiki ke hoʻolōʻihi i ke ola a me ka hoʻolaha ʻana i ka ʻelemakule olakino. Ua aʻo ʻia i loko o nā meaola like ʻole, a ua hōʻike nā hopena i ka hoʻonui ʻia o ke ola a me ka hoʻomaikaʻi ʻana i ke olakino.