ʻO Rosuvastatin Calcium CAS:147098-20-2 Mea Hana Mea Hoʻolako

ʻO Rosuvastatin calcium kahi mea hoʻopaʻa koho o ka HMG-CoA reductase. ʻO ka mea hoʻopaʻa HMG-CoA reductase ka enzyme e kaupalena ana i ka wikiwiki o ka hoʻololi hydroxy-3-methylglutaryl coenzyme A i valerate A (ʻO ka mea mua o ka cholesterol). ʻO ke kahua nui o ka hana o rosuvastatin ʻo ia ke akepaʻa - nā ʻōpū pahuhopu o ka hoʻohaʻahaʻa cholesterol. Hoʻonui ʻo Rosuvastatin i ka helu o nā mea loaʻa LDL hepatic ma ka ʻili o ke kelepona, e paipai ana i ka omo ʻana a me ka catabolism o LDL, e kāohi ana i ka synthesis hepatic o VLDL, a laila e hōʻemi ana i ka helu holoʻokoʻa o VLDL a me nā ʻāpana LDL. Hiki i ka Rosuvastatin calcium ke kāohi hoʻokūkū i ke akepaʻa methylglutaryl coenzyme A reductase, a hoʻokō hou i kona hopena maikaʻi i ka hōʻemi ʻana i ka momona. He lōʻihi ka hapalua ola. ʻAʻohe hopena koʻikoʻi o ke kāne a me ka makahiki o nā maʻi i ka metabolism o nā lāʻau lapaʻau.