ʻO Trt-Gly-OH CAS:5893-05-0

He kuleana koʻikoʻi ko Bz-His-OMe i ka synthesis peptide, e lawelawe ana ma ke ʻano he poloka hale koʻikoʻi no ke kūkulu ʻana i nā peptides me nā ʻano kūkulu a me nā hana kikoʻī. Hōʻoia ka hui pale benzyl e noho mau ana ke koena histidine i ka wā o nā kaʻina hana synthesis peptide, e ʻae ana i ka hui peptide pololei a kāohi ʻia. Eia kekahi, ʻo ke alo o ka hui methyl ester e hoʻopilikia i ka reactivity kemika a me nā pilina hydrophobic o ka peptide, e lilo ia i mea waiwai no ka hoʻolālā ʻana i nā peptides me ka permeability membrane i hoʻonui ʻia a i ʻole nā ​​​​​​mana kikoʻī. I ka hoʻomohala ʻana i ka lāʻau lapaʻau, hiki ke hoʻohana ʻia kēia hui e hana i nā lāʻau lapaʻau peptide me ka hoʻomaikaʻi ʻana i ke kūpaʻa a me ka bioavailability, hiki ke alakaʻi i ka hoʻonui ʻana i ka pono therapeutic. Ma waho aʻe o kāna kuleana i ka synthesis peptide, loaʻa iā Bz-His-OMe ka noi ma ka proteomics a me ka noiʻi biochemical, kahi e hiki ai ke hoʻohana ʻia e aʻo i nā pilina protein-protein, e noiʻi i nā hana enzymatic, a e ʻimi i nā loli conformational pH-dependent i nā protein. ʻO kona ʻano i hana ʻia e hiki ai i nā mea noiʻi ke noiʻi i nā intricacies o nā kaʻina hana cellular a me nā ʻano maʻi, e hāʻawi ana i nā holomua i ka hoʻomaopopo ʻana i ke olakino a me ka pathology. ʻO ka maʻalahi o ka hui a me ka kūlike me nā kūlana hoʻokolohua like ʻole e lilo ia i mea nui loa no ka wehe ʻana i nā paʻakikī o nā ʻōnaehana olaola a me ka hoʻomohala ʻana i nā hana i kuhikuhi ʻia no nā kūlana olakino like ʻole. I ka hōʻuluʻulu manaʻo, hōʻike ʻo Bz-His-OMe i kahi mea hana waiwai no nā mea noiʻi i ka peptide synthesis, ka hoʻomohala ʻana i nā lāʻau lapaʻau, a me nā haʻawina biochemical, e hāʻawi ana i ka hiki ke hoʻopilikino i nā peptides me nā waiwai kikoʻī a wehe i nā ʻano kumu o nā kaʻina hana olaola, a laila e kōkua ana i ka holomua i ka lāʻau lapaʻau a me ka biotechnology.