Wikamina B13 (Orotic Acid) CAS:65-86-1 Mea Hana Mea Hoʻolako

ʻO ka waikawa Orotic (ʻike ʻia hoʻi ʻo pyrimidinecarboxylic acid) he waikawa heterocyclic; ua ʻike ʻia hoʻi ʻo ia. Ma ka mōʻaukala, ua manaʻoʻiʻo ʻia ʻo ia kekahi hapa o ka hui huaora B a ua kapa ʻia ʻo ia he huaora B13, akā ua ʻike ʻia i kēia manawa ʻaʻole ia he huaora. Ua ʻike nui ʻia ʻo ia he mea mua i ka biosynthesis o pyrimidines; i loko o nā mammals ua hoʻokuʻu ʻia mai ka mitochondrial dihydroorotate dehydrogenase (DHODH) no ka hoʻololi ʻana i UMP e ka cytoplasmic UMP synthase enzyme. He ʻāpana maʻamau nō hoʻi ka OA o ka ʻai, i loaʻa i ka waiū a me nā huahana waiū, a ua hoʻololi ʻia i uridine no ka hoʻohana ʻana i ke ala pyrimidine salvage ma ke akepaʻa, nā puʻupaʻa a me nā erythrocytes.

Kauoha a Noi paha i ka ʻŌlelo Kūʻai

Nā kikoʻī huahana

Nā Lepili Huahana

Hoʻohana a me ka hopena

ʻO ka waikawa Orotic kahi waena i loko o ka biosynthesis pyrimidine de novo i hiki ke hoʻohana ʻia e aʻo i ke ʻano kikoʻī a me nā kinetics o ka orotate phosphoribosyltransferase (OPRT) e hoʻoulu ai i ka hoʻoili phosphoribosyl reversible mai 5?-phospho-α-d-ribose 1?-diphosphate (PRPP) i ka waikawa orotic (OA), e hana ana i ka pyrophosphate a me ka orotidine 5?-monophosphate (OMP). Hoʻohana ʻia ia ma ke ʻano he mea hoʻomaka no ka bioproduction kalepa hiki o ka uridine 5?-monophosphate (UMP) e nā microbes e like me Corynebacterium ammoniagenes (ATCC 6872) a i ʻole Saccharomyces cerevisiae. Hiki ke hoʻohana ʻia e aʻo i ke ala hōʻailona cell AMPK/SREBP-1 a me nā ʻano hana hoʻoponopono transcription e hoʻoulu ai i ka lipogenesis hepatic.

Laʻana Huahana

Hoʻopili Huahana:

ʻIke Hou Aʻe:

Hoʻonohonoho ʻana	C5H4N2O4
Hoʻāʻo	99%
helehelena	Pauka keʻokeʻo
Helu CAS.	65-86-1
Hoʻopili ʻana	25KG
Ola Papa	2 mau makahiki
Ka Waihona	E mālama i kahi maloʻo a me kahi anuanu
Palapala hōʻoia	ISO.