Z-Pro-NH2 CAS:34079-31-7

He mea nui ko Z-Pro-NH2 i ka kemika peptide no ka hana ʻana i nā peptides a me nā peptidomimetics. Ma ke ʻano he derivative amide L-proline i pale ʻia e N-Boc, hoʻomaʻalahi ia i ka hoʻokomo ʻana o nā koena proline i loko o nā kaulahao peptide, e ʻae ana i ka hoʻolālā ʻana i nā moʻo peptide maʻamau me nā waiwai kūkulu a me nā hana kikoʻī. Hilinaʻi nā kemika a me nā mea noiʻi iā Z-Pro-NH2 i ka synthesis peptide solid-phase a me solution-phase e hoʻokomo i nā motif proline, e hiki ai ke ʻimi i nā ʻano peptide hou no nā pilina i kuhikuhi ʻia me nā mea loaʻa olaola, nā enzymes, a me nā pahuhopu biomolecular ʻē aʻe. Eia kekahi, loaʻa iā Z-Pro-NH2 ka noi i ka hoʻomohala ʻana o nā peptidomimetics—nā mole i hoʻolālā ʻia e hoʻohālike i nā waiwai a me nā hana o nā peptides bioactive. Ma ka hoʻohana ʻana i nā ʻāpana i loaʻa iā Z-Pro-NH2, hiki i nā kānaka ʻepekema ke hana ʻenekinia i nā peptidomimetics me nā ʻano pharmacological like ʻole, e hāʻawi ana i ka hiki ke lilo i mau moho lāʻau lapaʻau hou, nā probes molecular, a me nā mea hana biochemical no nā noi therapeutic a me nā noiʻi. Eia kekahi, lawelawe ʻo Z-Pro-NH2 ma ke ʻano he ʻāpana koʻikoʻi i ka hana ʻana i nā lāʻau lapaʻau a me nā therapeutics e pili ana i ka peptide. ʻO kona maʻemaʻe kiʻekiʻe a me ka hilinaʻi e lilo ia i mea nui loa i ka hana ʻana o nā peptides maʻamau a me nā peptidomimetics no nā haʻawina preclinical a me nā lapaʻau, e hāʻawi ana i nā mea noiʻi me ka maʻalahi e hoʻopilikino i nā ʻano peptide e hoʻokō i ka hana olaola i hoʻonui ʻia, ke koho ʻana, a me nā waiwai pharmacokinetic. I ka hōʻuluʻulu manaʻo, hāʻawi nui ʻo Z-Pro-NH2 i ka holomua o ka kemika peptide, ka ʻike ʻana i nā lāʻau lapaʻau, a me ka hoʻomohala ʻana i nā lāʻau lapaʻau, e hāʻawi ana i nā ʻepekema a me nā mea noiʻi i nā ala e hoʻohana ai i nā hiki o nā peptides a me nā peptidomimetics no ka hoʻoponopono ʻana i nā pilikia olaola paʻakikī a me ka hoʻokele ʻana i ka hana hou therapeutic.