γ-L-Glutamyl-3-carboxy-4-nitroanilide, paʻakai monoammonium CAS: 63699-78-5

ʻO ka γ-L-Glutamyl-3-carboxy-4-nitroanilide, ʻo ka paʻakai monoammonium kahi substrate i hoʻohana pinepine ʻia i nā hoʻāʻo biochemical e ʻike a ana i ka hana o ka enzyme γ-glutamyl transpeptidase (GGT). ʻO GGT kahi enzyme i loaʻa i nā ʻiʻo like ʻole, me ke akepaʻa, nā puʻupaʻa, a me ka pancreas. Pili ia i ka haki ʻana a me ka metabolism o ka glutathione, kahi antioxidant koʻikoʻi i loko o nā cell.

Hoʻololi ʻia ka hui ʻana e GGT i loko o kahi huahana melemele, hiki ke helu ʻia ma ke ʻano spectrophotometrically ma kahi nalu kikoʻī. ʻO ka ikaika o ke kala e pili pono ana i ka hana GGT i loko o ka hāpana. ʻAe kēia i ke ana ʻana o nā pae hana GGT, hiki ke kōkua i ka loiloi ʻana i ka hana o ke akepaʻa a me ka ʻike ʻana i nā maʻi akepaʻa.

He mea pono ka hoʻohana ʻana o ka γ-L-Glutamyl-3-carboxy-4-nitroanilide, ka paʻakai monoammonium i nā hoʻāʻo GGT i nā ʻano like ʻole, me nā diagnostics lapaʻau, nā haʻawina noiʻi, a me ka hoʻomohala ʻana i nā lāʻau. Hiki iā ia ke nānā i ka hana GGT i nā laʻana o ka mea maʻi, e kōkua ana i ka ʻike a me ka loiloi ʻana i nā maʻi ate e like me ka maʻi ate ʻona, nā maʻi ʻaʻai ate, a me ka hōʻino ʻana o ka ate i hoʻoulu ʻia e ka lāʻau.