5′-O-Tritylthymidine CAS:7791-71-1 Kumukūʻai Mea Hana

ʻO 5′-O-Tritylthymidine kahi hua o ka thymidine, ʻo ia ka nucleoside i haku ʻia me ka pyrimidine base thymine i hoʻopili ʻia i kahi kō deoxyribose. ʻO ka hui trityl kahi hui pale i hoʻohana pinepine ʻia i ka synthesis organik e uhi i kahi hui hana reactive no kekahi manawa. I ke ʻano o 5′-O-Tritylthymidine, ua hoʻopili ʻia ka hui trityl i ka hui 5′ hydroxyl o ke kō deoxyribose o thymidine. Hoʻohana pinepine ʻia kēia hoʻololi ʻana i ka synthesis a me ka hoʻololi ʻana o nā waikawa nucleic, ʻoi aku hoʻi i loko o ke ʻano o ka synthesis DNA solid-phase. Hana ka hui trityl e pale i ka hui 5′ hydroxyl i ka wā o nā hopena kemika a hiki ke wehe koho ʻia ma lalo o nā kūlana akahai e hana i ka hui hydroxyl manuahi no nā manipulations ma hope. Loaʻa i kēia hui nā noi ma ke kahua o ka kemika waikawa nucleic a me ka synthesis oligonucleotide.